Two New C21 Steroidal Glycosides from the Roots of Cynanchum paniculatum.
- Yu HL et al (2019).
- Nat Prod Bioprospect.
- PubMed:
- 31028545
This study explored the potential of a traditional Chinese medicine, OC, for treating Alzheimer's disease. Using computer modeling, the researchers identified new compounds from OC that may improve oral bioavailability and blood-brain barrier permeability. These compounds were found to have multiple effects on AD-related pathways and processes, suggesting that they may have synergistic effects for treating AD. The study sheds light on the complex mechanisms of OC and highlights its potential as a multi-target therapy for AD.