Eupatilin inhibits microglia activation and attenuates brain injury in intracerebral hemorrhage.
The study aimed to investigate the effect of a flavone called eupatilin on inflammation caused by intracerebral hemorrhage (ICH)-induced brain injury. Eupatilin was found to significantly inhibit microglial migration and decrease the production of inflammatory cytokines. The study also found that eupatilin inhibited NF-κB activation in BV2 cells. The results suggest that eupatilin has neurological protective effects and could be used as a therapeutic target for ICH.
- Qiao HB et al (2018).
- Exp Ther Med.
- PubMed:
- 30344678