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The neuroprotective and antioxidant profiles of selenium-containing polysaccharides from the fruit of Rosa laevigata.

Researchers have developed a method for extracting and separating polysaccharides from Rosa laevigata fruit using microwave-assisted aqueous two-phase extraction. Two selenium-containing polysaccharides, Se-RLFP-1 and Se-RLFP-2, were isolated and found to have antioxidant properties, particularly at high concentrations. They were also found to have a neuroprotective effect against oxidative stress induced by HO in SH-SY5Y neuroblastoma cells, with Se-RLFP-1 exhibiting significant activity at a concentration of 100 μg/mL. These findings suggest that R. laevigata fruit and its polysaccharides may have potential health benefits.

Liu X et al (2018).
Food Funct.
PubMed:
29513319