All Studies

The water extract of tutsan (Hypericum androsaemum L.) red berries exerts antidepressive-like effects and in vivo antioxidant activity in a mouse model of post-stroke depression.

Hypericum androsaemum L., also known as tutsan, is a plant commonly grown for its ornamental value and has been used in traditional Portuguese and Spanish medicine to treat depression. In this study, researchers tested the water extract of its red berries (WE) in a mouse model of post-stroke depression. They found that the highest dose of WE significantly reduced depression symptoms and increased endogenous antioxidant defenses in the mouse brain. The study identified four bioactive compounds in WE, including shikimic acid and chlorogenic acid. This is the first study to demonstrate the protective effects of WE in post-stroke depression in vivo, which suggests that tutsan may have potential as an alternative treatment for depression.

Nabavi SM et al (2018).
Biomed Pharmacother.
PubMed:
29353203

Alkaloids Profiling of Fumaria capreolata by Analytical Platforms Based on the Hyphenation of Gas Chromatography and Liquid Chromatography with Quadrupole-Time-of-Flight Mass Spectrometry.

Contreras MDM et al (2017).
Int J Anal Chem.
PubMed:
29348751