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Antiepileptogenic and Neuroprotective Effects of Pergularia daemia on Pilocarpine Model of Epilepsy.

Researchers investigated the effects of a plant extract called PDR on epilepsy and neuroprotection. They conducted experiments on mice and rat brain cells and found that chronic oral administration of PDR increased the time it took for seizures to occur and improved memory. PDR also increased antioxidant and acetylcholinesterase activities in the hippocampus and increased survival rates of primary cortical neurons after being exposed to a toxin. These results suggest that PDR may have potential in treating epilepsy and protecting the brain from damage.

Kandeda AK et al (2017).
Front Pharmacol.
PubMed:
28713279