GeoBotanical: All Studies

18257.

Ruscogenin Attenuates Cerebral Ischemia-Induced Blood-Brain Barrier Dysfunction by Suppressing TXNIP/NLRP3 Inflammasome Activation and the MAPK Pathway.

Ruscogenin, a sapogenin from Ophiopogon japonicus, has been shown to protect against ischemic injury to the brain. Researchers investigated its effects on blood-brain barrier dysfunction after stroke and found that it decreased brain damage, improved neurological function, and increased blood flow in mice. In brain cells, ruscogenin increased cell viability, decreased leakage, and modulated tight junction expression. It also inhibited the expression of inflammatory markers and decreased reactive oxygen species generation. These findings suggest that ruscogenin has potential for preventing and treating stroke.

Cardiology Neuroscience Ophiopogon japonicus

Cao G et al (2016).; Int J Mol Sci.
DOI:: 10.3390/ijms17091418
PubMed:: 27589720

18258.

A water extract of Malva verticillata seeds suppresses osteoclastogenesis and bone resorption stimulated by RANK ligand.

Genetics Malva verticillata

Shim KS et al (2016).; BMC Complement Altern Med.
DOI:: 10.1186/s12906-016-1295-6
PubMed:: 27580958

18259.

Water-soluble extract of Saxifraga stolonifera has anti-tumor effects on Lewis lung carcinoma-bearing mice.

Cancer Saxifraga stolonifera

Liu D, Yang P and Zhang YQ (2016).; Bioorg Med Chem Lett.
DOI:: 10.1016/j.bmcl.2016.08.051
PubMed:: 27575479

18260.

Sensitivity of Candida albicans to essential oils: are they an alternative to antifungal agents?

Antimicrobial Genetics Phytochemistry Satureja montana

Bona E et al (2016).; J Appl Microbiol.
DOI:: 10.1111/jam.13282
PubMed:: 27568869

18261.

The effect of Bongardia Chrysogonum on prostate tissue in a rat model of STZ-induced diabetes.

Diabetes Bongardia chrysogonum

Dokuyucu R et al (2016).; Springerplus.
DOI:: 10.1186/s40064-016-2973-z
PubMed:: 27563517

18262.

The anti-arthritic, anti-inflammatory, antioxidant activity and relationships with total phenolics and total flavonoids of nine South African plants used traditionally to treat arthritis.

Immunology Phytochemistry Maesa lanceolata

Elisha IL et al (2016).; BMC Complement Altern Med.
DOI:: 10.1186/s12906-016-1301-z
PubMed:: 27554099

18263.

Essential oil components of orange peels and antimicrobial activity.

Antimicrobial Phytochemistry Citrus sinensis

Geraci A et al (2017).; Nat Prod Res.
DOI:: 10.1080/14786419.2016.1219860
PubMed:: 27535797

18264.

New Antiplasmodial Diterpenes from Gutierrezia sarothrae.

Phytochemistry Gutierrezia sarothrae

Su Q et al (2016).; Nat Prod Commun.
PubMed:: 27534100