Phytochemical and biological assessment of secondary metabolites isolated from a rhizosphere strain, Sphingomonas sanguinis DM of Datura metel.
- Awad MA et al (2024).
- BMC Complement Med Ther.
- PubMed:
- 38796482
Researchers isolated novel compounds from Bletilla striata tubers and found two that inhibit neuroinflammation by targeting the AKT/IκB/NF-κB pathway and PTP1B overexpression. Potential for treating neuroinflammatory diseases.
Researchers studied C. procera for potential anticancer properties. Extracts showed antiangiogenic and anticancer capabilities with minimal side effects. Identifying novel targets for liver cancer treatment. Important for developing innovative medications.
Oxymatrine from Sophora flavescens induces anti-tumor apoptosis in NSCLC cells by down-regulating TRIM46 and inhibiting the NF-κB pathway. This suggests potential for targeted cancer therapy.