All Studies

Novel phenanthrene/bibenzyl trimers from the tubers of Bletilla striata attenuate neuroinflammation via inhibition of NF-κB signaling pathway.

Researchers isolated novel compounds from Bletilla striata tubers and found two that inhibit neuroinflammation by targeting the AKT/IκB/NF-κB pathway and PTP1B overexpression. Potential for treating neuroinflammatory diseases.

Shao S et al (2024).
Chin J Nat Med.
PubMed:
38796217

Angiogenic protein profiling, phytochemical screening and in silico anti-cancer targets validation of stem, leaves, fruit, and seeds of Calotropis procera in human liver and breast cancer cell lines.

Researchers studied C. procera for potential anticancer properties. Extracts showed antiangiogenic and anticancer capabilities with minimal side effects. Identifying novel targets for liver cancer treatment. Important for developing innovative medications.

Khan MF et al (2024).
Environ Res.
PubMed:
38795948

Oxymatrine induces apoptosis in non-small cell lung cancer cells by downregulating TRIM46.

Oxymatrine from Sophora flavescens induces anti-tumor apoptosis in NSCLC cells by down-regulating TRIM46 and inhibiting the NF-κB pathway. This suggests potential for targeted cancer therapy.

Zhong Y et al (2024).
Toxicon.
PubMed:
38795848