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Coconut oil contains unique medium-chain fatty acids (MCFA) that are easily absorbed and metabolized by the liver and can convert to ketones, providing an alternative energy source for the brain. Evidence suggests that coconut may be beneficial in the treatment of obesity, dyslipidemia, elevated LDL, insulin resistance, hypertension, and Alzheimer's disease (AD). Coconut is rich in dietary fiber, vitamins, minerals, phenolic compounds, and hormones that may assist in preventing the aggregation of amyloid-β peptide, a key step in the pathogenesis of AD. The study explores the physiology of coconut and discusses its potential role as a therapeutic option for the prevention and management of AD. Coconut is considered a highly nutritious 'functional food.'
Curculigo orchioides (Kali Musli) is a plant known for its adaptogenic and anti-osteoporotic activities. This study evaluated its potential neuroprotective effect in animals treated with cyclophosphamide to induce neurotoxicity. The plant was extracted using methanol and phytochemical studies were performed. Results showed that C. orchioides at 400mg/kg significantly restored levels of catalase, superoxide dismutase, and glutathione as well as decreased levels of malondialdehyde. It was also observed that the plant extract is rich in phytochemicals such as flavonoids and polyphenols, which have a reputed neuroprotective effect. These findings suggest that C. orchioides may hold potential for the prevention or treatment of neurodegenerative disorders.