Flavonoids isolated from Rumex aquaticus exhibit neuroprotective and neurorestorative properties by enhancing neurite outgrowth and synaptophysin.

Researchers have isolated two flavonoids from the Rumex aquaticus plant, quercetin-3-O-galactoside and quercetin-3-O-arabinoside, which show promise in protecting brain cells from damage caused by ischemic stroke. The study used a rat cell line and found that the flavonoids significantly improved cell survival and neurite outgrowth in a model of ischemia. Additionally, one of the flavonoids was found to enhance the expression of synaptophysin, a marker of synapses and synaptic plasticity. These results suggest that the flavonoids could be useful in promoting stroke recovery by protecting and promoting the growth of brain cells.

Orbán-Gyapai O et al (2014).

CNS Neurol Disord Drug Targets.

PubMed:

25345505

Mutagenic and antimutagenic effects of Heterotheca inuloides.

Ruiz-Pérez NJ et al (2014).

Sci Rep.

DOI:

10.1038/srep06743

PubMed:

25339199

Anticholinesterase, antioxidant, and neuroprotective effects of Tripleurospermum disciforme and Dracocephalum multicaule.

In recent years, there has been renewed interest in using medicinal plants for drug development. This study explores the potential of these natural sources as candidates for new medicinal agents. While the implications of the study are broad, the focus is on the methods and results achieved, highlighting the power of the study.

Mandegary A et al (2014).

J Ayurveda Integr Med.

DOI:

10.4103/0975-9476.140474

PubMed:

25336847

Sex determination in dioecious Mercurialis annua and its close diploid and polyploid relatives.

Russell JR and Pannell JR (2015).

Heredity (Edinb).

DOI:

10.1038/hdy.2014.95

PubMed:

25335556

Ardisia crenata extract stimulates melanogenesis in B16F10 melanoma cells through inhibiting ERK1/2 and Akt activation.

Yao C et al (2015).

Mol Med Rep.

DOI:

10.3892/mmr.2014.2697

PubMed:

25333888

Molecular docking studies of anti-cancerous candidates in Hippophae rhamnoides and Hippophae salicifolia.

Usha T et al (2014).

J Biomed Res.

DOI:

10.7555/JBR.28.20130110

PubMed:

25332713

Antioxidant capacity and amino acid analysis of Caralluma adscendens (Roxb.) Haw var. fimbriata (wall.) Grav. & Mayur. aerial parts.

Maheshu V, Priyadarsini DT and Sasikumar JM (2014).

J Food Sci Technol.

DOI:

10.1007/s13197-012-0761-5

PubMed:

25328180

In vitro anticoagulant and antioxidant activities of Jatropha gossypiifolia L. (Euphorbiaceae) leaves aiming therapeutical applications.

Félix-Silva J et al (2014).

BMC Complement Altern Med.

DOI:

10.1186/1472-6882-14-405

PubMed:

25328027