Polyoxypregnane glycoside from Dregea volubilis extract inhibits IL-1β-induced expression of matrix metalloproteinase via activation of NF-κB in human chondrocytes.

Itthiarbha A et al (2012).

In Vitro Cell Dev Biol Anim.

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10.1007/s11626-011-9475-7

PubMed:

22179678

Inbreeding depression in Solanum carolinense (Solanaceae) under field conditions and implications for mating system evolution.

Researchers found that the weed Solanum carolinense can adjust the strength of its self-incompatibility (SI) system. Inbred plants produced fewer ramets than outbred plants, and suffered more herbivore damage. In year one, inbred plants showed 0.63% inbreeding depression (δ), which rose to 0.79% in year two. Outbred plants produced 2.5 times more ramets than inbred ones in year two. Overall, the weed has a total δ of 0.85, meaning it's not fully self-compatible, and its plasticity in the SI system is part of a mixed-mating system that allows self-fertilization when cross-pollination is lacking. This shows the importance of genetic diversity for successful reproduction and survival.

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PLoS One.

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PubMed:

22174810

Effect of sesquiterpene lactone coronopilin on leukaemia cell population growth, cell type-specific induction of apoptosis and mitotic catastrophe.

Cotugno R et al (2012).

Cell Prolif.

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10.1111/j.1365-2184.2011.00796.x

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22168177

Hypolipidemic Activity of Eryngium carlinae on Streptozotocin-Induced Diabetic Rats.

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Molecules.

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22146374

A New Flavonoid C-Glycoside from Celtis australis L. and Celtis occidentalis L. Leaves and Potential Antioxidant and Cytotoxic Activities.

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Sci Pharm.

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22145118

Antihyperlipidemic potential of Cedrus deodara extracts in monosodium glutamate induced obesity in neonatal rats.

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Indian J Pharmacol.

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22144766

Pteridium aquilinum and its ptaquiloside toxin induce DNA damage response in gastric epithelial cells, a link with gastric carcinogenesis.

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22143989