All Studies

Flow cytometry: Unravelling the real antimicrobial and antibiofilm efficacy of natural bioactive compounds.

FCM used to test essential oils on Listeria and E. coli. FCM better than plate-count method for counting viable bacteria. Flow cytometry critical for food microbiology and monitoring antimicrobial effectiveness.

Poscente V et al (2024).
J Microbiol Methods.
PubMed:
38759758

A single-cell profile reveals the transcriptional regulation responded for Abelmoschus manihot (L.) treatment in diabetic kidney disease.

HKC, from Abelmoschus manihot, treats diabetic kidney disease. Key flavonoids in HKC include rutin, hyperoside, and quercetin. Important for DKD treatment.

Wu C et al (2024).
Phytomedicine.
PubMed:
38759315

Matrine induces autophagic cell death by triggering ROS/AMPK/mTOR axis and apoptosis in multiple myeloma.

Matrine from a Chinese herb induces autophagy in multiple myeloma cells, leading to cell death. Combining with rapamycin enhances anti-tumor activity. Potential therapeutic strategy targeting ROS/AMPK/mTOR axis.

Li X et al (2024).
Biomed Pharmacother.
PubMed:
38759291

Semisynthesis and biological evaluation of novel honokiol thioethers against colon cancer cells HCT116 via inhibiting the transcription and expression of YAP protein.

Novel honokiol thioether 3k, derived from a traditional Chinese medicine, showed superior anticancer activity against colon cancer cells. Inhibits cell proliferation and induces cell death by directly inhibiting YAP protein expression. Could be a promising anticancer candidate.

Yang R et al (2024).
Bioorg Med Chem.
PubMed:
38759254