The antimicrobial activity of essential oils of Hypericum scabrum, Hypericum scabroides and Hypericum triquetrifolium.
- Kizil G et al (2004).
- Phytother Res.
- PubMed:
- 15162373
A study screened extracts from various plant species for anticholinesterase activity on two enzymes, AChE and BChE, known to be involved in Alzheimer's disease. At a concentration of 10 microg/ml, none of the extracts showed any significant inhibitory activity. However, at a concentration of 1 mg/ml, extracts from Rhododendron ponticum subsp. ponticum, Rhododendron luteum, Corydalis solida subsp. solida, Glaucium corniculatum, and Buxus sempervirens showed remarkable inhibitory activity above 50% on AChE. Rhododendron ponticum subsp. ponticum, Corydalis solida subsp. solida, and Buxus sempervirens were the most active extracts against BChE. Fumaria extracts were highly potent inhibitors against both enzymes. This study suggests that these plant extracts have potential medicinal value in Alzheimer's disease treatment.