Alkaloids of the root-bark of Orixa japonica Thunb. V. On the structure of Kokusagine.
- TERASAKA M, OHTA T and NARAHASHI K (1954).
- Pharm Bull.
- PubMed:
- 13215027
In this study, researchers tested the potential for an herbal extract called Dipsacus asper to protect against cognitive impairment caused by chronic exposure to aluminum chloride in rats. The animals showed significant declines in memory and increases in beta-amyloid protein, a hallmark of Alzheimer's disease, after 90 days of exposure to aluminum chloride. Treatment with Dipsacus asper or vitamin E for up to five months improved the rats' performance on memory tasks and reduced the levels of beta-amyloid in their brains. The researchers suggest that Dipsacus asper may have therapeutic benefits for Alzheimer's disease.