Binding of quinolizidine alkaloids to nicotinic and muscarinic acetylcholine receptors.

Researchers investigated the affinity of 14 quinolizidine alkaloids for nicotinic and/or muscarinic acetylcholine receptors. They found that N-methylcytisine and cytisine had the highest affinity at the nicotinic receptor, while certain types of quinolizidine alkaloids were particularly active at the muscarinic receptor. This study suggests that these compounds could potentially be used to develop drugs targeting these receptors.

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Genetics of male sterility in gynodioecious Plantago coronopus. I. Cytoplasmic variation.

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Genetics.

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7789775

Triterpenoid saponins from Clematis chinensis.

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Phytochemistry.

PubMed:

7786477

Anguivine and isoanguivine, steroid alkaloid glycosides from Solanum anguivi.

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Phytochemistry.

PubMed:

7766005

Triterpenoid glycosides from Anagallis arvensis.

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Phytochemistry.

PubMed:

7765757

Triterpenoid saponins from Dianthus chinensis.

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Phytochemistry.

PubMed:

7764590

An oleanolic acid based bisglycoside from Clematis montana roots.

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Phytochemistry.

PubMed:

7764156

Flavonoids and a saponin from Spartium junceum.

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Phytochemistry.

PubMed:

7764155