GeoBotanical: All Studies

2129.

Self Emulsifying Delivery System of Cissus quadrangularis: Evidence of Enhanced Efficacy and Promising Pharmacokinetic Profile in the Management of Osteoporosis.

Arthritis Cissus quadrangularis

Garg J et al (2024).; AAPS PharmSciTech.
DOI:: 10.1208/s12249-024-02821-x
PubMed:: 38730121

2130.

Transcriptome analysis reveals that trehalose alleviates chilling injury of peach fruit by regulating ROS signaling pathway and enhancing antioxidant capacity.

Genetics Immunology Prunus persica

Wang X et al (2024).; Food Res Int.
DOI:: 10.1016/j.foodres.2024.114331
PubMed:: 38729716

2131.

The role of polydatin in inhibiting oxidative stress through SIRT1 activation: A comprehensive review of molecular targets.

Researchers studied the medicinal plant Reynoutria japonica Houtt, known for its diverse pharmacological properties. Major bioactive constituents are polydatin and resveratrol. Important for Traditional Chinese Medicine uses.

Immunology Reynoutria japonica

Liu K et al (2024).; J Ethnopharmacol.
DOI:: 10.1016/j.jep.2024.118322
PubMed:: 38729537

2132.

Chitosan nanoemulsion incorporated with Carum carvi essential oil as ecofriendly alternative for mitigation of aflatoxin B(1) contamination in stored herbal raw materials.

Phytochemistry Carum carvi Withania somnifera

Das S et al (2024).; Int J Biol Macromol.
DOI:: 10.1016/j.ijbiomac.2024.132248
PubMed:: 38729502

2133.

Selective impact of three homogenous polysaccharides with different structural characteristics from Grifola frondosa on human gut microbial composition and the structure-activity relationship.

Gastroenterology Grifola frondosa

Bai G et al (2024).; Int J Biol Macromol.
DOI:: 10.1016/j.ijbiomac.2024.132143
PubMed:: 38729493

2134.

Achyranthes bidentata polysaccharide ameliorates type 2 diabetes mellitus by gut microbiota-derived short-chain fatty acids-induced activation of the GLP-1/GLP-1R/cAMP/PKA/CREB/INS pathway.

ABP polysaccharide improves gut microbiota in T2DM mice, increasing SCFAs and GLP-1 levels, activating GLP-1/INS pathway. Potential T2DM therapeutic candidate.

Diabetes Gastroenterology Achyranthes bidentata

Xia T et al (2024).; Int J Biol Macromol.
DOI:: 10.1016/j.ijbiomac.2024.132256
PubMed:: 38729481

2135.

Ficus platyphylla alleviates seizure severity and neurobehavioral comorbidities in pentylenetetrazole-kindled rats via modulation of oxidative stress.

Researchers studied the effects of Ficus platyphylla extract on seizure severity, cell degeneration, and behavioral changes in PTZ-kindled rats. FP reduced these effects, suggesting potential treatment for epilepsy and neuropsychiatric comorbidities.

Immunology Neuroscience Ficus platyphylla

Chindo BA et al (2024).; Brain Res.
DOI:: 10.1016/j.brainres.2024.148994
PubMed:: 38729331

2136.

Mechanism of action of Sambucus williamsii Hance var. miquelii in the treatment of osteoporosis analyzed by UHPLC-HRMS/MS combined network pharmacology and experimental validation.

Arthritis Sambucus williamsii

Mu L et al (2024).; Fitoterapia.
DOI:: 10.1016/j.fitote.2024.106003
PubMed:: 38729247