All Studies

Antitumor mechanisms and future clinical applications of the natural product triptolide.

Triptolide (TPL) from a Chinese herb shows promise for fighting cancer, but its mechanism is unclear and its toxicity limits use. Research is underway to better understand how TPL works and improve its clinical application for treating tumors.

Cancer Tripterygium wilfordii
Bao S et al (2024).
Cancer Cell Int.
DOI:
10.1186/s12935-024-03336-y
PubMed:
38678240

Structural characterization of the polysaccharide from the black crystal region of Inonotus obliquus and its effect on AsPC-1 and SW1990 pancreatic cancer cell apoptosis.

IOP1-1, a polysaccharide from Inonotus obliquus, inhibits pancreatic cancer cell growth and induces apoptosis through multiple pathways. Potential adjuvant for cancer treatment.

Cancer Inonotus obliquus
Ding M et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.131891
PubMed:
38677687

Bioactive components in Psidium guajava extracts elicit biotoxic attributes and distinct antioxidant enzyme modulation in the larvae of vectors of lymphatic filariasis and dengue.

Guava leaf extracts show promise as eco-friendly mosquito larvicides. Methanol extract most effective. Contains bioactive compounds that target mosquitoes' enzymes. Consider for alternative vector control methods.

Immunology Psidium guajava
Aremu HK et al (2024).
Exp Parasitol.
DOI:
10.1016/j.exppara.2024.108766
PubMed:
38677581

The Power of Punica granatum: A Natural Remedy for Oxidative Stress and Inflammation; a narrative review.

Pomegranate has numerous health benefits, such as managing hypertension, dyslipidemia, hyperglycemia, and insulin resistance. Its antioxidant and anti-inflammatory properties also enhance wound healing and infection resistance.

Immunology Punica granatum
Moradnia M et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.118243
PubMed:
38677577

Plantaginis Semen ameliorates diabetic kidney disease via targeting the sphingosine kinase 1/sphingosine-1-phosphate pathway.

Researchers studied the medicinal properties of Plantaginis Semen (PS) in China for diuretic, anti-hypertensive, anti-hyperlipidemic, and anti-hyperglycemic effects. Limited research on its therapeutic mechanisms warrants further investigation.

Diabetes Plantago asiatica
Lan JP et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.118221
PubMed:
38677576

A novel isoquinoline alkaloid HJ-69 isolated from Zanthoxylum bungeanum attenuates inflammatory pain by inhibiting voltage-gated sodium and potassium channels.

Scientists studied isoquinoline alkaloids in Z. bungeanum for potential medicinal benefits. This plant has traditional use for arthritis and toothache in Asia. Research may lead to new treatments.

ImmunologyNeurosciencePainPhytochemistry Zanthoxylum bungeanum
Wang L et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.118218
PubMed:
38677570

Salvia miltiorrhiza Bge. processed with porcine cardiac blood inhibited GLRX5-mediated ferroptosis alleviating cerebral ischemia-reperfusion injury.

Researchers studied the effects of processed Danshen (DS) with porcine cardiac blood (PCB-DS) on Cerebral ischemia-reperfusion injury (CIRI) in strokes. PCB-DS showed potential anti-ischemic effects, but the mechanism is still unknown.

Cardiology SalviaSalvia miltiorrhiza
Zhou S et al (2024).
Phytomedicine.
DOI:
10.1016/j.phymed.2024.155622
PubMed:
38677272

Restoring bone-fat equilibrium: Baicalin's impact on P38 MAPK pathway for treating diabetic osteoporosis.

Baicalin from Scutellaria baicalensis helps treat diabetic osteoporosis by promoting bone formation and inhibiting fat accumulation. Its effects may be mediated through the P38-MAPK pathway, offering a potential new treatment approach.

ArthritisDiabetesImmunology Scutellaria baicalensis
Qin W et al (2024).
Biomed Pharmacother.
DOI:
10.1016/j.biopha.2024.116571
PubMed:
38677248
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