All Studies

The functional and structural characterisation of the bZIP transcription factors from Myristica fragrans Houtt. associated to plant disease-resistant defence: An insight from transcriptomics and computational modelling.

Sarmah P et al (2024).
Int J Biol Macromol.
PubMed:
38670182

Protective effects of ginsenoside F(2) on isoproterenol-induced myocardial infarction by activating the Nrf2/HO-1 and PI3K/Akt signaling pathways.

GF, found in ginseng, has various health benefits but its impact on heart attacks is unclear. Study investigates potential role in myocardial infarction.

Cui Y et al (2024).
Phytomedicine.
PubMed:
38669969

Ethanolic extract of Arctium lappa leaves alleviates cerebral ischemia reperfusion-induced inflammatory injury via HDAC9-mediated NF-κB pathway.

Arctium lappa leaves may help treat ischemic stroke by reducing inflammatory response, potentially improving patient outcomes. Worth exploring further in lab research.

Wang M et al (2024).
Phytomedicine.
PubMed:
38669967

Polyphyllin I induces rapid ferroptosis in acute myeloid leukemia through simultaneous targeting PI3K/SREBP-1/SCD1 axis and triggering of lipid peroxidation.

Polyphyllin I (PPI), from Paris polyphylla, exhibits strong cytotoxicity on AML cells via ferroptosis induction. PPI targets PI3K/SREBP-1/SCD1 axis and triggers lipid peroxidation, with potential to enhance erastin-induced ferroptosis. PPI is a PI3K inhibitor, inhibits tumor progression, and prolongs survival in mice.

Zhou X et al (2024).
J Nat Med.
PubMed:
38668832