Brusatol hinders the progression of bladder cancer by Chac1/Nrf2/SLC7A11 pathway.

Brusatol from Brucea javanica inhibits bladder cancer growth by inducing ferroptosis through the Chac1/Nrf2/SLC7A11 pathway, showing promise as a potential antineoplastic drug.

Yu XI et al (2024).

Exp Cell Res.

DOI:

10.1016/j.yexcr.2024.114053

PubMed:

38663476

Exploring the antifungal potential of Annona muricata leaf extract-loaded hydrogel in treating vulvovaginal candidiasis.

Study developed innovative hydrogel containing Annona muricata extract to control Candida albicans in vulvovaginal candidiasis. Extract increased polymer interactions, decreased viscosity, and showed efficacy in reducing fungal burden and inflammation. Potential natural therapeutic option for treatment.

Campos LM et al (2024).

Colloids Surf B Biointerfaces.

DOI:

10.1016/j.colsurfb.2024.113919

PubMed:

38663311

Purple sweet potato polysaccharide ameliorates concanavalin A-induced hepatic injury by inhibiting inflammation and oxidative stress.

Ding X and Fan S (2024).

Phytomedicine.

DOI:

10.1016/j.phymed.2024.155652

PubMed:

38663118

The effects of Atractylodes macrocephala extract BZEP self-microemulsion based on gut-liver axis HDL/LPS signaling pathway to ameliorate metabolic dysfunction-associated fatty liver disease in rats.

Li B et al (2024).

Biomed Pharmacother.

DOI:

10.1016/j.biopha.2024.116519

PubMed:

38663104

Ameliorative effects of elderberry (Sambucus nigra L.) extract and extract-derived monosaccharide-amino acid on H2O2-induced decrease in testosterone-deficiency syndrome in a TM3 Leydig cell.

Elderberry extract and FL improve testosterone production and reduce oxidative stress in Leydig cells. Potential natural alternative to testosterone-replacement therapy for age-related testosterone-deficiency syndrome.

Lee S et al (2024).

PLoS One.

DOI:

10.1371/journal.pone.0302403

PubMed:

38662754

The genotype of barley cultivars influences multiple aspects of their associated microbiota via differential root exudate secretion.

Pacheco-Moreno A et al (2024).

PLoS Biol.

DOI:

10.1371/journal.pbio.3002232

PubMed:

38662644

Crocin, the compound of the dried stigma of Crocus sativus L (saffron), restores doxorubicin-induced disturbances in kidney functioning, oxidative stress, inflammation, renal tissue morphology and TGF-β signalling pathways.

Altinoz E et al (2024).

Nat Prod Res.

DOI:

10.1080/14786419.2024.2344180

PubMed:

38662441

Noni enhances the anticancer activity of cyclophosphamide and suppresses myelotoxicity and hepatotoxicity in tumor-bearing mice.

Noni juice may prevent cancer by stopping harmful chemicals from damaging DNA. In a study, noni juice was found to have anti-tumor effects when used with a chemotherapy drug.

Ali M et al (2024).

J Cancer Res Clin Oncol.

DOI:

10.1007/s00432-024-05734-1

PubMed:

38662247