Exploring the effective components of honey-processed licorice (Glycyrrhiza uralensis Fisch.) in attenuating Doxorubicin-induced myocardial cytotoxicity by combining network pharmacology and in vitro experiments.

Study found honey-processed licorice (HPL) has stronger heart protection than raw licorice. Material basis and mechanism still unclear. Relevant for clinical use of traditional Chinese herb.

Sun P et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2024.118178

PubMed:

38604511

Highly oxidized rearranged derivatives of quinochalcone C-glycosides from Carthamus tinctorius.

Zhang H et al (2024).

Phytochemistry.

DOI:

10.1016/j.phytochem.2024.114094

PubMed:

38604325

Rapid identifying of COX-2 inhibitors from turmeric (Curcuma longa) by bioaffinity ultrafiltration coupled with UPLC-Q Exactive-Orbitrap-MS and zebrafish-based in vivo validation.

Lan Z et al (2024).

Bioorg Chem.

DOI:

10.1016/j.bioorg.2024.107357

PubMed:

38604020

Ziyuglycoside II attenuated OVX mice bone loss via inflammatory responses and regulation of gut microbiota and SCFAs.

Zhou Y et al (2024).

Int Immunopharmacol.

DOI:

10.1016/j.intimp.2024.112027

PubMed:

38603860

Edible wild plants, chicory and purslane, alleviated diabetic testicular dysfunction, and insulin resistance via suppression 8OHdg and oxidative stress in rats.

Chicory and purslane herbal extracts improve testicular function in diabetic rats by reducing blood sugar, lipid levels, inflammation, and oxidative stress while enhancing sperm, hormone levels, and testicular health. Promising for potential human applications.

Saad EA et al (2024).

PLoS One.

DOI:

10.1371/journal.pone.0301454

PubMed:

38603728

Solanum nigrum Toxicity and Its Neuroprotective Effect Against Retinal Ganglion Cell Death Through Modulation of Extracellular Matrix in a Glaucoma Rat Model.

Researchers investigated the neuroprotective effects of extract on retinal ganglion cells in a glaucoma rat model. Results show potential for novel neurotherapeutics to treat glaucoma by reducing oxidative stress and remodeling matrix metalloproteinases.

Yadav KS et al (2024).

J Ocul Pharmacol Ther.

DOI:

10.1089/jop.2023.0089

PubMed:

38603587

Lactuca sativa L. Extract Enhances Sleep Duration Through Upregulation of Adenosine A1 Receptor and GABA(A) Receptors Subunits in Pentobarbital-Injected Mice.

Researchers found that Lactuc extracts improved sleep in mice by increasing adenosine A1 receptor and GABA receptor subunit expression in the brain. This suggests Lactuc could be used to develop natural sleep aids.

Lee M et al (2024).

J Med Food.

DOI:

10.1089/jmf.2023.K.0250

PubMed:

38603571

Interactions between Salivary Proteins and Apple Polyphenols and the Fate of Complexes during Gastric Digestion.

Berkel Kasikci M et al (2024).

J Agric Food Chem.

DOI:

10.1021/acs.jafc.4c00468

PubMed:

38603459