All Studies

Thrombin-induced platelet inhibition by 2',4'-dihydroxychalcone and 2',4'-dihydroxydihydrochalcone is mediated by inhibition of ROS production and Thromboxane synthase a activity: structure-activity relationship of polyphenol secondary metabolites from Empetrum nigrum.

The researchers tested compounds for inhibiting platelet activation by targeting ROS, TxS, and cyclic nucleotide pathways. Compounds and showed significant inhibition, key for potential use with P2Y12 inhibitors. Identifying new ways to control platelet activation is important for preventing clot-related diseases.

Phytochemistry Empetrum nigrum
Fock E et al (2024).
Nat Prod Res.
DOI:
10.1080/14786419.2024.2334882
PubMed:
38567701

Rosa laevigata Polysaccharides Ameliorate Dextran Sulfate Sodium-induced Ulcerative Colitis of Beagles through Regulating Gut Microbiota.

RLP from Rosa laevigata Michx. helps treat ulcerative colitis in beagles by protecting the intestinal barrier and balancing gut bacteria. This may have implications for UC treatment in humans.

Gastroenterology Rosa laevigata
Peng S et al (2024).
Chem Biodivers.
DOI:
10.1002/cbdv.202302102
PubMed:
38567653

Chemical characterisation of essential oil from Sambucus williamsii Hance leaves and its hepatoprotective effects.

Essential oil from Hance leaves protects liver from injury by reducing enzymes indicating liver damage, inhibiting oxidative stress and inflammation, and modulating TLR4/NF-κB pathways. Potential treatment for liver injuries.

Phytochemistry Sambucus williamsii
Meng X et al (2024).
Nat Prod Res.
DOI:
10.1080/14786419.2024.2327637
PubMed:
38567651

Antidepressant and anxiolytic potential of Citrus reticulata Blanco essential oil: a network pharmacology and animal model study.

Study on Blanco essential oil (CBEO) shows fast-acting antidepressant and anxiolytic effects. Identifies active compounds, optimal dosage, and duration for therapy. Important for potential treatment of depression and anxiety.

NeurosciencePhytochemistry Citrus reticulata
Khanh Nguyen NP et al (2024).
Front Pharmacol.
DOI:
10.3389/fphar.2024.1359427
PubMed:
38567354

Phenolic Content, Antioxidant Potential, and Antimicrobial Activity of Uvaria chamae (Annonaceae), a Food Plant from Burkina Faso.

Researchers evaluated antioxidant, antibacterial properties of leaf extracts from Burkina Faso. Fractions showed high phenolic content, antioxidant activity, and antibacterial effects on foodborne pathogens. Extracts may be used as supplements to enhance immunity and combat bacterial infections.

AntimicrobialImmunologyPhytochemistry Uvaria chamae
Kaboré K et al (2024).
Biochem Res Int.
DOI:
10.1155/2024/1289859
PubMed:
38567288

Phytochemical characterization, antimicrobial and antioxidant activities of Terminalia catappa methanol and aqueous extracts.

WHO study found 80% use herbal medicine, 40% of drugs from plants. Terminalia catappa leaves show antimicrobial/antioxidant properties. Benefits traditional medicine and drug development.

AntimicrobialImmunologyPhytochemistry Terminalia catappa
Mwangi WC et al (2024).
BMC Complement Med Ther.
DOI:
10.1186/s12906-024-04449-7
PubMed:
38566161

Combined sensory, volatilome and transcriptome analyses identify a limonene terpene synthase as a major contributor to the characteristic aroma of a Coffea arabica L. specialty coffee.

Study links specific molecular differences to aromatic profile of specialty coffees, helping distinguish high value market produce. Important for producers and consumers seeking unique coffee flavors.

GeneticsPhytochemistry Coffea arabica
Marie L et al (2024).
BMC Plant Biol.
DOI:
10.1186/s12870-024-04890-3
PubMed:
38566027

DNA methylation regulates the secondary metabolism of saponins to improve the adaptability of Eleutherococcus senticosus during drought stress.

Researchers investigated drought stress effects on plant growth and secondary metabolite synthesis, focusing on DNA methylation changes in Eleutherococcus senticosus. Results highlighted DNA demethylation's role in gene expression and saponin synthesis for plant adaptation to drought stress.

GeneticsPhytochemistry Eleutherococcus senticosus
Wang S et al (2024).
BMC Genomics.
DOI:
10.1186/s12864-024-10237-x
PubMed:
38565995
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