Dichroa febrifuga Lour.: A review of its botany, traditional use, phytochemistry, pharmacological activities, toxicology, and progress in reducing toxicity.

Scientists studied the toxic plant Dichroa febrifuga Lour., often used in traditional Chinese medicine as a treatment for malaria and parasitic diseases. Results may provide insights for future drug development.

Wang M et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2024.118093

PubMed:

38537842

Oxymatrine alleviates high-fat diet/streptozotocin-induced non-alcoholic fatty liver disease in C57BL/6 J mice by modulating oxidative stress, inflammation and fibrosis.

Lou D et al (2024).

Biomed Pharmacother.

DOI:

10.1016/j.biopha.2024.116491

PubMed:

38537582

Cuscuta chinensis flavonoids alleviate ovarian damage in offspring female mice induced by BPA exposure during pregnancy by regulating the central carbon metabolism pathway.

Pregnant mice exposed to BPA can have reproductive damage in female offspring. CCFs mitigate this damage by regulating central carbon metabolism pathways and reducing oxidative stress. This study informs on potential BPA reproductive damage treatments.

Zhao Q et al (2024).

Ecotoxicol Environ Saf.

DOI:

10.1016/j.ecoenv.2024.116253

PubMed:

38537475

Withaferin A, a natural thioredoxin reductase 1 (TrxR1) inhibitor, synergistically enhances the antitumor efficacy of sorafenib through ROS-mediated ER stress and DNA damage in hepatocellular carcinoma cells.

Chen X et al (2024).

Phytomedicine.

DOI:

10.1016/j.phymed.2023.155317

PubMed:

38537439

Advancing green extraction of bioactive compounds using deep eutectic solvent-based ultrasound-assisted matrix solid-phase dispersion: Application to UHPLC-PAD analysis of alkaloids and organic acids in Coptidis rhizoma.

Han M et al (2024).

Talanta.

DOI:

10.1016/j.talanta.2024.125983

PubMed:

38537350

Pharmacological and immunomodulatory modes of action of medically important phytochemicals against arthritis: A molecular insight.

Study finds potential benefits of medicinal plants like Curcuma longa, Syzygium aromaticum, and Zingiber officinale in treating rheumatoid arthritis due to antioxidant and anti-inflammatory properties, offering safer alternative to conventional treatments.

Aqsa et al (2024).

Mol Biol Rep.

DOI:

10.1007/s11033-024-09386-9

PubMed:

38536526

Cloning and functional mechanism of the dwarf gene gba affecting stem elongation and cellulose biosynthesis in jute (Corchorus olitorius).

Li Q et al (2024).

Plant J.

DOI:

10.1111/tpj.16724

PubMed:

38536089

New Analytical Approach to Quinolizidine Alkaloids and Their Assumed Biosynthesis Pathways in Lupin Seeds.

Scientists analyzed quinolizidine alkaloids in wild lupin seeds to understand their potential pharmacological uses. Method developed and pathway for alkaloid biosynthesis explored. Impact on future legume crop development.

Namdar D et al (2024).

Toxins (Basel).

DOI:

10.3390/toxins16030163

PubMed:

38535829