All Studies

Soursop leaf extract and fractions protects against L-NAME-induced hypertension and hyperlipidemia.

Study showed leaf extracts have potential anti-hypertensive and antihyperlipidemic properties. Important for potential new treatments for high blood pressure and high cholesterol.

Nsor OO et al (2024).
Front Nutr.
PubMed:
39171117

Association mapping and candidate gene identification for yield traits in European hazelnut (Corylus avellana L.).

Researchers conducted a genome-wide study on European hazelnuts, identifying 189 genetic markers associated with desirable traits. This information can be used to improve hazelnut breeding and understand the genetic basis of important characteristics.

Baytar AA et al (2024).
Plant Direct.
PubMed:
39170862

Genome-wide identification and analysis of the EIN3/EIL gene family in broomcorn millet (Panicum miliaceum L.).

Study on gene family in broomcorn millet and reveals key evolutionary characteristics and expression patterns under stress. Provides valuable insights for future polyploid studies and ethylene signaling pathway research.

Yang M et al (2024).
Front Plant Sci.
PubMed:
39170780

Exploring sesquiterpene lactone as a dual therapeutic agent for diabetes and oxidative stress: insights into PI3K/AKT modulation.

Artemisinin shows potential for anti-diabetic and antioxidant effects by targeting the PI3K/AKT pathway. It inhibits enzymes related to hyperglycaemia and exhibits antioxidant properties without toxicity in zebrafish models. This suggests a promising therapy for diabetes and oxidative stress.

Velumani K et al (2024).
3 Biotech.
PubMed:
39170770

CKD-497 inhibits NF-kB signaling and ameliorates inflammation and pulmonary fibrosis in ovalbumin-induced asthma and particulate matter-induced airway inflammatory diseases.

CKD-497, derived from rhizome and fruits, reduces inflammation and mucus production in asthma and pollution-induced lung inflammation. It inhibits proinflammatory cytokines and NF-kB pathway, potentially protecting against respiratory diseases.

Kim H et al (2024).
Front Pharmacol.
PubMed:
39170711

The beneficial pharmacological effects of Uncaria rhynchophylla in neurodegenerative diseases: focus on alkaloids.

Summary: Traditional Chinese medicine Gouteng shows neuroprotective benefits in neurodegenerative diseases like Parkinson's and Alzheimer's. Compounds like corynoxine B offer potential for new drug development. Relevant for aging population health.

Chen L, Liu Y and Xie J (2024).
Front Pharmacol.
PubMed:
39170707

Schisandrin C enhances type I IFN response activation to reduce tumor growth and sensitize chemotherapy through antitumor immunity.

Schisandrin C activates the cGAS-STING pathway, inhibiting tumor growth in breast and colon cancer models. It enhances type I IFN response and antitumor immunity, improving chemotherapy efficacy. Important for future cancer treatment strategies.

Yang H et al (2024).
Front Pharmacol.
PubMed:
39170700

Investigation of bioactive phytochemical compounds of the Ethiopian medicinal plant using GC-MS and FTIR.

Study on medicinal plant extracts for treating warts showed presence of various bioactive compounds with anti-bacterial, analgesic, anti-inflammatory properties. Effective against gram-positive bacteria. Traditional therapy uses this plant for wart treatment.

Adem Endris Y, Abdu KY and Abate SG (2024).
Heliyon.
PubMed:
39170564