Biofabricated Green Synthesized Hibiscus Silver Nanoparticles Potentiate Antibacterial Activity and Cytotoxicity in Human Lung Cancer Cells.

Hibiscus sabdariffa plant extract was used to create stable silver nanoparticles with antibacterial, cytotoxic, and anti-inflammatory properties. Further research is needed to explore their potential as medicines.

Ahirwar B et al (2024).

Appl Biochem Biotechnol.

DOI:

10.1007/s12010-024-04901-x

PubMed:

38483765

Structurally Diverse Bisbenzylisoquinoline Alkaloids with Antiadipogenic Activity through PPARγ Downregulation from the Embryo of Nelumbo nucifera Seeds.

Unknown compounds isolated from seeds' embryos have antiadipogenic effects by downregulating key receptors. Configurations in alkaloids enhance activity. Potential for antiobesity treatments with further research.

Zhang P et al (2024).

J Nat Prod.

DOI:

10.1021/acs.jnatprod.3c01290

PubMed:

38483204

Enhancing fluconazole reactivation against Candida auris: efficacy of Cinnamomum zeylanicum essential oil versus cinnamaldehyde.

Di Vito M et al (2024).

Microbiol Spectr.

DOI:

10.1128/spectrum.00176-24

PubMed:

38483141

Celastrol Ameliorates Neuronal Mitochondrial Dysfunction Induced by Intracerebral Hemorrhage via Targeting cAMP-Activated Exchange Protein-1.

Celastrol protects neurons by improving mitochondrial function and blocking cell death pathways in ICH-induced secondary brain injury. Targeting EPAC-1 with celastrol shows promise as a therapeutic strategy.

Li X Sr et al (2024).

Adv Sci (Weinh).

DOI:

10.1002/advs.202307556

PubMed:

38482725

Network Pharmacology Along with Molecular Docking to Explore the Mechanism of Danshen Injection against Anthracycline-induced Cardiotoxicity and Transcriptome Validation.

Researchers investigated how Danshen injection (DSI) can help reduce anthracycline-induced cardiotoxicity (AIC). Understanding this mechanism could lead to safer and more effective cancer therapies using anthracyclines.

Dai Q et al (2024).

Curr Pharm Des.

DOI:

10.2174/0113816128289845240305070522

PubMed:

38482629

Antibacterial and Antioxidant Efficacies of Secondary Metabolites from the Roots of Cyphostemma adenocaule: A Combined In Vitro and In Silico Study.

Study isolated compounds from plant traditionally used for medicinal purposes. Compounds showed potent antioxidant and antibacterial activities, with potential for drug development. Traditional medicine supported by scientific evidence.

Gebrehiwot H et al (2024).

J Trop Med.

DOI:

10.1155/2024/1679695

PubMed:

38482509

Gypenoside induces apoptosis by inhibiting the PI3K/AKT/mTOR pathway and enhances T-cell antitumor immunity by inhibiting PD-L1 in gastric cancer.

Gypenoside induces apoptosis in gastric cancer cells, inhibits PI3K/AKT/mTOR pathway, and reduces PD-L1 expression. Enhances antitumor immunity of T cells. Potential new therapeutic agent for immunotherapy in gastric cancer.

Wu H et al (2024).

Front Pharmacol.

DOI:

10.3389/fphar.2024.1243353

PubMed:

38482051

Evaluation of Antioxidant, Anti-inflammatory, and Antimicrobial Activities of Raspberry Fruit Extract: An In Vitro Study.

Raspberry extract has strong antimicrobial, antioxidant, and anti-inflammatory properties, making it a promising natural remedy for oral health issues like mucosal lesions, cancer, and candidiasis. Additional studies are needed to confirm its potential benefits.

Gomathi R, Umamaheswari TN and Prethipa R (2024).

Cureus.

DOI:

10.7759/cureus.54045

PubMed:

38481926