An arabinose-rich heteropolysaccharide isolated from Belamcanda chinensis (L.) DC treats liver cancer by targeting FAK and activating CD40.

BCP80-2 polysaccharide from Belamcanda chinensis inhibits tumor growth, metastasis, and angiogenesis in zebrafish. It suppresses cell migration via FAK pathway and boosts immune response.

Zhao Y et al (2024).

Carbohydr Polym.

DOI:

10.1016/j.carbpol.2024.121831

PubMed:

38388048

Herbal medicines provide regulation against iron overload in cardiovascular diseases: Informing future applications.

Scientists studied the impact of iron levels on cardiovascular diseases and found that iron overload can worsen conditions like cardiomyopathy and atherosclerosis. They are also researching the use of herbal medicines to regulate iron levels and potentially treat these diseases.

Liu J et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2024.117941

PubMed:

38387684

Anti-papillary thyroid carcinoma effects of dioscorea bulbifera L. through ferroptosis and the PI3K/AKT pathway based on network pharmacology and experimental validation.

Study examines DBL effects on PTC. DBL, a Chinese medicine, shows potential for treating thyroid cancer. Research could lead to new, effective therapies.

Gao Y et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2024.117912

PubMed:

38387682

Geniposide from Gardeniae Fructus exerts antipyretic effect in febrile rats through modulating the TLR4/NF-κB signaling pathway.

Li M et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2024.117934

PubMed:

38387681

DbGTi: Thermostable trypsin inhibitor from Dioscorea bulbifera L. ground tubers: assessment of antioxidant and antibacterial properties and cytotoxicity evaluation using zebrafish model.

Jegadheeshwari S et al (2024).

Int J Biol Macromol.

DOI:

10.1016/j.ijbiomac.2024.130244

PubMed:

38387638

Microbiological and metabolic pathways analysing the mechanisms of alfalfa polysaccharide and sulfated alfalfa polysaccharide in alleviating obesity.

Alfalfa polysaccharide and sulfated alfalfa polysaccharide help combat obesity by regulating gut bacteria and metabolic pathways. Specific modifications target different pathways for potential therapeutic use.

Li Z et al (2024).

Int J Biol Macromol.

DOI:

10.1016/j.ijbiomac.2024.130334

PubMed:

38387635

The role of stinging nettle (Urtica dioica L.) in the management of rotenone-induced Parkinson's disease in rats.

Stinging Nettle supplement showed neuroprotective effects in a rat model of Parkinson's disease, reducing apoptosis, inflammation, oxidative stress, and improving clearance of alpha-synuclein deposits. Nettle could be a promising treatment for PD.

Albadawi E et al (2024).

Tissue Cell.

DOI:

10.1016/j.tice.2024.102328

PubMed:

38387425

Rare flavanone-diarylheptanoid hybrids from Typha angustifolia shows anti breast cancer activity via activating TGF-β1/Smad signaling pathway.

Scientists discovered new compounds from Typha angustifolia pollen with potential anti-cancer properties. These compounds induce cell death, arrest cell cycle, and inhibit migration & invasion in breast cancer cells by activating the TGF-β1 signaling pathway. Animal studies also showed promising anti-breast cancer activity.

Li YP et al (2024).

Eur J Med Chem.

DOI:

10.1016/j.ejmech.2024.116220

PubMed:

38387332