All Studies

Effectiveness of Ya-Samarn-Phlae in diabetic wound healing: Evidence from in vitro studies and a multicenter randomized controlled clinical trial.

Traditional Thai medicine Ya-Samarn-Phlae (YaSP) used for wounds, particularly diabetic foot ulcers. Study validates clinical use, identifies chemical markers, and evaluates wound healing properties. Important for evidence-based medicine and development of new treatments.

Sanpinit S et al (2024).
J Ethnopharmacol.
PubMed:
38373661

Valerenic acid attenuates pathological myocardial hypertrophy by promoting the utilization of multiple substrates in the mitochondrial energy metabolism.

Researchers studied valerenic acid (VA) in Valeriana officinalis L. for its potential in treating pathological myocardial hypertrophy (PMH) with positive results. VA's regulatory effect on the cardiovascular system could provide new treatment options for cardiac diseases.

Liu T et al (2024).
J Adv Res.
PubMed:
38373650

The basic chemical substances of total alkaloids of Uncaria rhynchophylla and their anti-neuroinflammatory activities.

Scientists identified new alkaloids in , which showed promising anti-neuroinflammatory effects by inhibiting NO production in microglial cells. Compounds , , , , , , and were particularly effective, with IC values of 5.87-76.78 M.

Qin JX et al (2024).
J Asian Nat Prod Res.
PubMed:
38373226

Critical review on anti-inflammation effects of saponins and their molecular mechanisms.

Saponins from plants and marine life show promise for anti-inflammatory therapies via molecular actions like NF-κB regulation. They shape the gut microbiome, impacting immune regulation and metabolic health, suggesting potential dietary interventions for chronic inflammation.

Wijesekara T, Luo J and Xu B (2024).
Phytother Res.
PubMed:
38372176

An integrated in vitro approach on the enzymatic and antioxidant mechanisms of four commercially available essential oils (Copaifera officinalis, Gaultheria fragrantissima, Helichrysum italicum, and Syzygium aromaticum) traditionally used topically for their anti-inflammatory effects.

Cebollada P et al (2024).
Front Pharmacol.
PubMed:
38371914

Synergistic anti-diabetic effect of phloroglucinol and total procyanidin dimer isolated from Vitisvinifera methanolic seed extract potentiates via suppressing oxidative stress: in-vitro evaluation studies.

Researchers identified and purified phloroglucinol and total procyanidin dimer from seed extract, showing superior anti-diabetic effects in vitro by enhancing glucose uptake and suppressing oxidative stress. This natural remedy could offer a safe and economical alternative to current diabetes treatments.

Thupakula S et al (2024).
3 Biotech.
PubMed:
38371900