Brucea javanica derived exosome-like nanovesicles deliver miRNAs for cancer therapy.

Exosome-like nanovesicles from B. javanica (BF-Exos) delivered microRNAs to cancer cells, slowing growth and metastasis. BF-Exos also inhibited angiogenesis. Promising for TNBC treatment.

Yan G et al (2024).

J Control Release.

DOI:

10.1016/j.jconrel.2024.01.060

PubMed:

38295998

Assessment of antimicrobial, antidiabetic, and anti-inflammatory properties of acetone extract of Aerva lanata (L.) by in-vitro approach and bioactive compounds characterization.

Acetone extract of Aerva lanata plant showed strong antimicrobial activity, significant antidiabetic effect, and moderate anti-inflammatory action. It contains bioactive molecules with potential pharmaceutical value for biomedical applications.

Shanmuganathan R et al (2024).

Environ Res.

DOI:

10.1016/j.envres.2024.118348

PubMed:

38295976

Dehydrocostus lactone suppresses gastric cancer progression by targeting ACLY to inhibit fatty acid synthesis and autophagic flux.

Dehy, a compound from Saussurea lappa Clarke, effectively treats cancer and gastrointestinal disorders. However, its specific impact on gastric cancer is not well-known.

Chen Y et al (2024).

J Adv Res.

DOI:

10.1016/j.jare.2024.01.028

PubMed:

38295877

Convergent evolution of water-conducting cells in Marchantia recruited the ZHOUPI gene promoting cell wall reinforcement and programmed cell death.

Lu YT et al (2024).

Curr Biol.

DOI:

10.1016/j.cub.2024.01.014

PubMed:

38295796

Forsythia suspensa polyphenols regulate macrophage M1 polarization to alleviate intestinal inflammation in mice.

Lv W et al (2024).

Phytomedicine.

DOI:

10.1016/j.phymed.2024.155336

PubMed:

38295660

Synergistic effects and molecular mechanisms of DL-3-n-butylphthalide combined with dual antiplatelet therapy in acute ischemic stroke.

Combining DL-3-n-butylphthalide (NBP) and dual antiplatelet therapy (DAPT) improves acute ischemic stroke in rats. It reduces neurological deficits, infarct area, and inflammation by suppressing the pyroptosis-inflammation pathway in brain tissues, especially in microglial cells.

Du Y et al (2024).

Int Immunopharmacol.

DOI:

10.1016/j.intimp.2024.111592

PubMed:

38295546

A Review of the Ethnobotany, Biological Activity, and Phytochemistry of the Plants in the Gundelia Genus.

Mehrzadeh M et al (2024).

Chem Biodivers.

DOI:

10.1002/cbdv.202301932

PubMed:

38294082

In silico ADMET and anti-inflammatory profiles of the stigmast-4-en-3-one and isolation of isovanillin as the antioxidant principle of Imperata cylindrica (L.) P. Beauv.

Razafindrakoto ZR et al (2024).

Nat Prod Res.

DOI:

10.1080/14786419.2024.2305649

PubMed:

38293732