All Studies

Ameliorative Potential of Pumpkin Seed Oil (Cucurbita pepo L.) Against Tramadol-Induced Oxidative Stress.

Tossers studied the toxic effects of tramadol, a pain medication, which is commonly used but lacks regulation. The research aims to understand how to protect against its toxicity.

Ekpono EU et al (2024).
Dose Response.
PubMed:
38234695

Polyherbal extract improves glycometabolic control in alloxan-induced diabetic rats via down-regulating the MAPK/JNK pathway, modulating Nrf-2/Keap-1 expression, and stimulating insulin signaling.

The researchers looked at a mix of plants to see if it has antioxidant and antidiabetic effects in a diabetes model. This information may be useful for managing diabetes and exploring natural remedies.

Aslam B et al (2024).
Iran J Basic Med Sci.
PubMed:
38234664

Safranal acts as a neurorestorative agent in rats with cerebral ischemic stroke via upregulating SIRT1.

Safranal, an active compound in saffron, reduces brain damage after ischemic stroke (IS) by reducing oxidative stress. It promotes neuron survival, stimulates neurogenesis, induces angiogenesis, and increases SIRT1 expression. Silencing SIRT1 reverses these effects. Safranal shows promise for restoring neural function after IS.

He F et al (2023).
Exp Ther Med.
PubMed:
38234630

Isolation, structure modification, and anti-rheumatoid arthritis activity of isopimarane-type diterpenoids from Orthosiphon aristatus.

Researchers identified new compounds from a herb and created derivatives. The compounds displayed anti-rheumatoid arthritis activity and inhibited inflammatory proteins.

Luo YX et al (2024).
J Enzyme Inhib Med Chem.
PubMed:
38234133

Basic helix-loop-helix (bHLH) gene family in rye (Secale cereale L.): genome-wide identification, phylogeny, evolutionary expansion and expression analyses.

Study analyzed the bHLH transcription factor family in rye, a hardy crop plant, to understand its role in plant development and stress responses. This knowledge can be useful for improving crop resilience and yield.

Chen X et al (2024).
BMC Genomics.
PubMed:
38233751

Pumpkin seeds (Cucurbita pepo subsp. ovifera) decoction promotes Trichinella spiralis expulsion during intestinal phase via "Weep and Sweep" mechanism.

This study tested the impact of pumpkin decoction on Trichinella spiralis in mice. Pumpkin decoction, especially when combined with honey, significantly reduced adult worm count, improved immune response, and decreased histological changes. Pumpkin decoction could be a promising alternative treatment for T. spiralis.

Saleh AS et al (2024).
Sci Rep.
PubMed:
38233460

Purple Sweet Potato Polysaccharide Exerting an Anti-inflammatory Effect via a TLR-Mediated Pathway by Regulating Polarization and Inhibiting the Inflammasome Activation.

Song D et al (2024).
J Agric Food Chem.
PubMed:
38233194