All Studies

Transcriptome analysis reveals cadmium exposure enhanced the isoquinoline alkaloid biosynthesis and disease resistance in Coptis chinensis.

Study identifies molecular mechanisms behind cadmium accumulation in medicinal herb Coptis chinensis, offers strategies to control and mitigate accumulation, enhance resistance, and promote synthesis of secondary metabolites.

Li X et al (2024).
Ecotoxicol Environ Saf.
PubMed:
38218103

Hypersampsonone H attenuates ulcerative colitis via inhibition of PDE4 and regulation of cAMP/PKA/CREB signaling pathway.

Researchers investigated the effects of a compound named HS-1, found in a Chinese herbal medicine, on ulcerative colitis (UC). Results suggest that HS-1 has potential therapeutic benefits for UC by reducing inflammation. Further studies are needed for confirmation.

Li Y et al (2024).
Int Immunopharmacol.
PubMed:
38218008

A strategy of accuracy quantification by extending the concentration monitoring coverage based on online double collision energy of ultra-high performance liquid chromatography tandem mass spectrometry: The pharmacokinetics of Toddalia asiatica as a case study.

Scientists developed a method called ODCE with UHPLC-MS/MS to measure compounds in traditional Chinese medicines. This strategy allows for wider range quantification and is useful for monitoring the effectiveness and safety of TCMs.

Wang R et al (2024).
J Chromatogr A.
PubMed:
38217962

Transcription factor LBD16 targets cell wall modification/ion transport genes in peach lateral root formation.

PpLBD16, a transcription factor in peach plants, promotes root formation by activating genes related to cell wall synthesis, ion transport, and peach root organogenesis. Understanding its regulatory network can enhance LR development.

Wu X et al (2024).
Plant Physiol.
PubMed:
38217865

In Silico Insights into Micro-Mechanism Understanding of Extracts of Taxus Chinensis Fruits Against Alzheimer's Disease.

Researchers investigated the potential of taxus chinensis fruit (TCF) in treating Alzheimer's disease (AD). They identified the constituents and targets associated with AD. Relevant for potential AD treatment.

Chen M et al (2024).
J Alzheimers Dis.
PubMed:
38217605

Discovery of bi-4-methoxycarbonyl-2-quinolone and evaluation of its anti-inflammatory and anti-cancer activity in vitro.

A new alkaloid compound with anti-inflammatory and anti-cancer properties was discovered, along with six known alkaloids, holding promise for potential therapeutic applications in inflammation and cancer treatment.

Wang W et al (2024).
Nat Prod Res.
PubMed:
38217490

Two novel alkaloids from Portulaca oleracea L. and their anti-inflammatory bioactivities.

Two new alkaloids, Oleracrylimide D and Oleracrylimide E, were discovered in L. Their structures were identified using spectroscopic methods, and their anti-inflammatory properties were investigated using ELISA.

Wang C et al (2024).
Nat Prod Res.
PubMed:
38217487