Automatic annotation of the bHLH gene family in plants.
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The compound azadiradione found in Neem seeds has shown potential in improving synaptic function by increasing expression of Ube3a, parvalbumin, and BDNF. This suggests a possible role in treating neuropsychiatric/neurodegenerative disorders.
Researchers investigated the effects of higenamine, found in Fuzi herb, on depression. Higenamine improved the dysfunction of gap junctions between astrocytes and reduced neuroinflammation. This suggests higenamine may be a potential treatment for neuropsychiatric disorders, including depression.
DHHP, a Chinese herb pair, relieves myocardial ischemia in rats by regulating gut microbiota. It improves diversity and increases beneficial bacteria while reducing harmful bacteria, offering potential for MI treatment.
This study identified three prenylflavonoids from leaves that show potential against SARS-CoV-2. The compounds have structural similarities to a ligand of the virus' Papain-Like Protease and successfully bind to its active pocket. Further research is needed to confirm their effectiveness and safety.