Biosensor-based active ingredient recognition system for screening potential small molecular Severe acute respiratory syndrome coronavirus 2 entry blockers targeting the spike protein from Rugosa rose.

Researchers identified gallic acid (GA) and methyl gallate (MG) from Rosa rugosa in Hanchuan zupa granules as inhibitors of the spike receptor-binding domain of SARS-CoV-2. These compounds block virus entry and have potential for COVID-19 treatment.

Yu W et al (2024).

Biomed Chromatogr.

DOI:

10.1002/bmc.5987

PubMed:

39126351

Modulation of Breast Cancer Cell Apoptosis and Macrophage Polarization by Mistletoe Lectin in 2D and 3D Models.

Korean mistletoe lectin (VCA) enhances breast cancer cell apoptosis by influencing M1 and M2 macrophage polarization. Results suggest potential for VCA as an anti-cancer agent.

Hong CE and Lyu SY (2024).

Int J Mol Sci.

DOI:

10.3390/ijms25158459

PubMed:

39126027

German Chamomile (Matricaria chamomilla L.) Flower Extract, Its Amino Acid Preparations and 3D-Printed Dosage Forms: Phytochemical, Pharmacological, Technological, and Molecular Docking Study.

Koshovyi O et al (2024).

Int J Mol Sci.

DOI:

10.3390/ijms25158292

PubMed:

39125862

Genome-Wide Analysis and Expression Profiling of Lectin Receptor-like Kinase Genes in Watermelon (Citrullus lanatus).

Lv D et al (2024).

Int J Mol Sci.

DOI:

10.3390/ijms25158257

PubMed:

39125826

Response of Soil Microbiota, Enzymes, and Plants to the Fungicide Azoxystrobin.

Baćmaga M, Wyszkowska J and Kucharski J (2024).

Int J Mol Sci.

DOI:

10.3390/ijms25158104

PubMed:

39125673

A Novel Strategy for Glioblastoma Treatment by Natural Bioactive Molecules Showed a Highly Effective Anti-Cancer Potential.

Researchers studied natural compounds, such as , , and , for treating aggressive brain tumor GBM. These compounds reduced tumor growth, migration, inflammation, and oxidative stress, offering a promising alternative to traditional treatments for better patient outcomes.

Giammona A et al (2024).

Nutrients.

DOI:

10.3390/nu16152389

PubMed:

39125270

Chitosan/Hyaluronate Complex-Coated Electrospun Poly(3-hydroxybutyrate) Materials Containing Extracts from Melissa officinalis and/or Hypericum perforatum with Various Biological Activities: Antioxidant, Antibacterial and In Vitro Anticancer Effects.

New fibrous materials were created from poly(3-hydroxybutyrate), HA, Ch, MO, and HP extracts using electrospinning. They showed high antioxidant, antibacterial, and anticancer properties, making them valuable for cancer therapy and wound dressings.

Anastasova I et al (2024).

Polymers (Basel).

DOI:

10.3390/polym16152105

PubMed:

39125132

Antioxidant and Antidiabetic Activity of Cornus mas L. and Crataegus monogyna Fruit Extracts.

Three green extraction methods were evaluated for polyphenols and vitamin C extraction from fruit extracts, with ASE and LE showing highest yields and antioxidant and antidiabetic activities. These extracts stimulate insulin secretion and could be beneficial for metabolic disorders.

Paun G et al (2024).

Molecules.

DOI:

10.3390/molecules29153595

PubMed:

39125000