HSP70, adiponectin, leptin, pro-inflammatory cytokines and metabolic hormones of heat-stressed broilers fed herbal supplements.
- Jimoh OA et al (2023).
- J Therm Biol.
- PubMed:
- 37633071
Polyphyllin VII (PPVII), a compound found in Paris polyphylla, can inhibit gastric cancer (GC) by inducing autophagy-mediated ferroptosis. PPVII activates the ULK1 pathway, inhibits the activity of the protein TOPK, and stabilizes its inactive form, suggesting PPVII could be a potential treatment for GC.
This study evaluated the cytotoxic activity of plant and herbal essential oils (EOs) against lung and colon cancer cells. The most potent EOs were encapsulated into solid lipid nanoparticles (SLN) to enhance their anticancer activity. SLN/CnEO was found to be safe and significantly increased cancer cell death and inhibition of cell migration.
L. Britt. leaf extracts contain rosmarinic acid, which exhibits potent cytotoxic effects on prostate cancer cells and interacts with multiple targets and pathways involved in prostate cancer. These findings suggest a potential use of L. Britt. leaves or their metabolites in prostate cancer treatment and prevention.