Houttuynia cordata is a herbal compound from China with anti-inflammatory, antiviral, and antioxidant properties. It can potentially help in asthma treatment by targeting NLRP3 inflammasome.
Umbelliprenin, a compound found in Artemisia absinthium L., has demonstrated its ability to induce apoptosis and exhibit antitumor effects in different types of cancers. However, its potential role in treating human pancreatic cancer remains unclear. Investigating the antitumor effect of umbelliprenin specifically in pancreatic cancer could provide valuable insights into potential therapeutic options for this challenging disease.
Researchers developed a highly efficient cultivation technology for hydroponic cuttings of a medicinal herb. It increases seedling production rate and addresses issues in traditional cultivation methods. However, the callus formation mechanism in hydroponic cuttings is still unclear.
In this study, researchers explored the mechanism behind the anti-cancer effects of L. rhizome extracts (KGEs). They found that KGEs inhibit the proliferation of Ehrlich ascites tumor cells by impacting cell cycle progression. The main component of KGEs, ethyl-methoxycinnamate (EMC), also displayed anti-proliferative effects. Additionally, EMC affected the expression of key proteins involved in cell cycle regulation, such as cyclin D1 and p21. Importantly, the study demonstrated that EMC and KGEs can suppress the growth of ascites fluid in mice with EATC. These findings provide valuable insights into the potential therapeutic applications of KGEs and EMC in cancer treatment.