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This study looks at the causes and treatments of fatigue in multiple sclerosis (MS). Researchers compared conventional medicine to Persian medicine (PM) and found that PM suggests the use of neurotonic herbs to alleviate fatigue by reinforcing the brain. The herbs, such as ashwagandha and ginseng, have antioxidant and anti-inflammatory properties that may be helpful in treating fatigue. Further studies are needed to confirm their effectiveness. Fatigue is a common symptom of MS and can be a significant barrier to daily activities.