Review

Phytocompounds of Rheum emodi, Thymus serpyllum, and Artemisia annua Inhibit Spike Protein of SARS-CoV-2 Binding to ACE2 Receptor: In Silico Approach.

Scientists studied the potential of plant compounds to bind to the spike proteins of SARS-CoV-2 and its variants, as well as to the host receptors the virus uses to enter cells. They performed computer simulations and found that artemisinin had the strongest binding affinity with the spike proteins and was stable in simulations. Emodin had the best interactions with the host receptors. Both compounds were non-toxic. These results suggest that these plant compounds could inhibit SARS-CoV-2 infection and warrant further investigation as potential COVID-19 therapies.

Rolta R et al (2021).
Curr Pharmacol Rep.
PubMed:
34306988