Review

The medicinal chemistry of Urtica dioica L.: from preliminary evidence to clinical studies supporting its neuroprotective activity.

Stinging nettle, a commonly found plant, has been used for various purposes including nutrition, cosmetics, and pharmacology. Its bioactive chemical constituents have been studied for their therapeutic applications. Research shows that compounds found in stinging nettle can provide neuroprotective effects, which could be used to develop tools against neurodegenerative diseases. This review highlights the computational, in vitro, pre-clinical and clinical data supporting the therapeutic applications of stinging nettle and its potential implications for neurodegenerative diseases.

Neuroscience Urtica dioica
Semwal P et al (2023).
Nat Prod Bioprospect.
DOI:
10.1007/s13659-023-00380-5
PubMed:
37171512

An overview of natural products that modulate the expression of non-coding RNAs involved in oxidative stress and inflammation-associated disorders.

This review discusses the role of oxidative stress and inflammation in various diseases and highlights natural products that target non-coding RNAs to combat these disorders. Several natural products, including Baicalein, Curcumin, and Resveratrol, are effective in controlling oxidative stress and inflammation. Other compounds, such as Peppermint and Gingerol, show potential in treating these disorders but their effect on non-coding RNAs is unknown. Further research in this area will be valuable in developing natural compounds for therapy.

Immunology Zanthoxylum bungeanum
Ngum JA et al (2023).
Front Pharmacol.
DOI:
10.3389/fphar.2023.1144836
PubMed:
37168992

A comprehensive review on clinically proven natural products in the management of nerve pain, with mechanistic insights.

Researchers investigated the use of non-pharmacological interventions for neuropathic pain as an alternative to current drugs. Their findings may offer more effective and safer treatment options for patients.

Pain Vitex agnus-castus
Dewanjee S et al (2023).
Heliyon.
DOI:
10.1016/j.heliyon.2023.e15346
PubMed:
37159686

Use of Lavandula angustifolia essential oil as a complementary therapy in adult health care: A scoping review.

Lavender essential oil has numerous beneficial properties like sedative, antidepressant, and antifungal effects. Researchers are studying its action mechanism to enhance patient well-being.

Phytochemistry Lavandula angustifolia
de Melo Alves Silva LC et al (2023).
Heliyon.
DOI:
10.1016/j.heliyon.2023.e15446
PubMed:
37153408

Potential antitumor activity of garlic against colorectal cancer: focus on the molecular mechanisms of action.

Garlic compounds have potential as cancer-fighting agents in colorectal cancer. Consuming garlic may help prevent colorectal cancer.

CancerGastroenterology Allium sativum
Oravetz K et al (2023).
Eur J Nutr.
DOI:
10.1007/s00394-023-03166-0
PubMed:
37140645

Opium alkaloids, biosynthesis, pharmacology and association with cancer occurrence.

This review focuses on the diverse alkaloids found in L. (Papaveraceae) and their extraction methods, particularly for morphine and codeine. It also explores the link between opium consumption and cancer.

CancerPhytochemistry Papaver somniferum
Vadhel A et al (2023).
Open Biol.
DOI:
10.1098/rsob.220355
PubMed:
37132222

Sinapis Semen: A review on phytochemistry, pharmacology, toxicity, analytical methods and pharmacokinetics.

Sinapis Semen (SS) is a traditional Chinese medicinal material with various pharmacological effects. This review summarizes its active ingredients, pharmacology, and toxicity, highlighting its potential in treating cough, asthma, inflammation, and more. Sinapine and sinapic acid are its main active components, but caution is needed due to its skin irritation potential. This research can guide future studies and support safe clinical applications of SS.

Phytochemistry Sinapis alba
Dang R, Guan H and Wang C (2023).
Front Pharmacol.
DOI:
10.3389/fphar.2023.1113583
PubMed:
37124205

Sanhua decoction: Current understanding of a traditional herbal recipe for stroke.

Sanhua decoction (SHD), a traditional Chinese medicine with over 40 bioactive compounds, shows promise in treating ischemic stroke by suppressing inflammation, protecting the blood brain barrier, inhibiting apoptosis, scavenging oxygen free radicals, and more. Large-scale clinical trials are needed to confirm its efficacy and understand its mechanisms.

CardiologyNeuroscience Citrus aurantiumHansenia weberbaueriana
Zheng L et al (2023).
Front Neurosci.
DOI:
10.3389/fnins.2023.1149833
PubMed:
37123364
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