Supercritical CO(2) Plant Extracts Show Antifungal Activities against Crop-Borne Fungi.
- Schoss K et al (2022).
- Molecules.
- PubMed:
- 35164398
Scientists are exploring the use of phytochemicals from medicinal plants as potential therapies against SARS CoV-2 and other coronaviruses. They created a library of 110 phytochemicals from different plants and found that ashwagandha and shatavari contained steroidal saponins and alkaloids that could potentially inhibit the virus's hemagglutinin-acetylesterase (HE) glycoprotein receptor. Molecular docking and dynamics simulations suggest that these phytochemicals could mask the active site of the receptor, preventing viral entry into host cells. This approach has potential for developing therapies against future deadly coronaviruses.