Antimicrobial Studies

Evaluation of the in vitro and in vivo antimicrobial activity of alkaloids prepared from Chelidonium majus L. using MRSA- infected C. elegans as a model host.

Researchers extracted alkaloids from Chelidonium majus L. and found they have strong antibacterial properties, particularly against MRSA. Alkaloids also extended the lifespan of C. elegans under stress through the DAF-2/DAF-16 pathway. This research could lead to new antibiotics and insights into immune responses.

AntimicrobialPhytochemistry Chelidonium majus
Qi J et al (2024).
Fitoterapia.
DOI:
10.1016/j.fitote.2024.105944
PubMed:
38580033

Assessment of metabolome diversity in black and white pepper in response to autoclaving using MS- and NMR-based metabolomics and in relation to its remote and direct antimicrobial effects against food-borne pathogens.

Study dissected pepper metabolome using H-NMR, identified 18 metabolites including piperine. Aroma profiling showed abundance of β-caryophyllene. Autoclaving improved pepper aroma and revealed antimicrobial activity against food-borne bacteria.

AntimicrobialPhytochemistry Piper nigrum
Baky MH et al (2024).
RSC Adv.
DOI:
10.1039/d4ra00100a
PubMed:
38572341

Evaluation of Free Radical Scavenging and Antimicrobial Activity of Coleus amboinicus-Mediated Iron Oxide Nanoparticles.

Iron oxide nanoparticles synthesized with stem extract showed high antimicrobial and antioxidant activity, making them a potential natural alternative to commercial drugs for various diseases.

Antimicrobial Coleus amboinicus
Kunjan F, Shanmugam R and Govindharaj S (2024).
Cureus.
DOI:
10.7759/cureus.55472
PubMed:
38571817

Nano-CeO(2) activates physical and chemical defenses of garlic (Allium sativum L.) for reducing antibiotic resistance genes in plant endosphere.

Researchers found that nano-CeO reduced antibiotic-resistant genes in garlic plants, potentially limiting spread to humans. Effective use of nanomaterials could help control antibiotic resistance in agriculture. The study suggests a potential solution to prevent the spread of antibiotic resistance in plants.

AntimicrobialGenetics Allium sativum
Xu Y et al (2024).
Ecotoxicol Environ Saf.
DOI:
10.1016/j.ecoenv.2024.116289
PubMed:
38570269

Antimicrobial and antibiofilm effect of cannabinoids from Cannabis sativa against methicillin-resistant Staphylococcus aureus (MRSA) causing bovine mastitis.

Researchers identified Cannabis sativa L. as a potent inhibitor of MRSA, with cannabidiol and Δ9-THC showing bactericidal action. This plant-based alternative may help combat antimicrobial resistance in bovine biofilm-associated MRSA infections.

Antimicrobial Azadirachta indicaCannabis sativaCarica papayaCurcuma longaEucalyptusMangifera indicaSyzygium cuminiTinospora cordifolia
Roshan M et al (2024).
Int Microbiol.
DOI:
10.1007/s10123-024-00505-x
PubMed:
38568425

Phenolic Content, Antioxidant Potential, and Antimicrobial Activity of Uvaria chamae (Annonaceae), a Food Plant from Burkina Faso.

Researchers evaluated antioxidant, antibacterial properties of leaf extracts from Burkina Faso. Fractions showed high phenolic content, antioxidant activity, and antibacterial effects on foodborne pathogens. Extracts may be used as supplements to enhance immunity and combat bacterial infections.

AntimicrobialImmunologyPhytochemistry Uvaria chamae
Kaboré K et al (2024).
Biochem Res Int.
DOI:
10.1155/2024/1289859
PubMed:
38567288

Phytochemical characterization, antimicrobial and antioxidant activities of Terminalia catappa methanol and aqueous extracts.

WHO study found 80% use herbal medicine, 40% of drugs from plants. Terminalia catappa leaves show antimicrobial/antioxidant properties. Benefits traditional medicine and drug development.

AntimicrobialImmunologyPhytochemistry Terminalia catappa
Mwangi WC et al (2024).
BMC Complement Med Ther.
DOI:
10.1186/s12906-024-04449-7
PubMed:
38566161

In vitro suppression of porcine epidemic diarrhea virus by Panax notoginseng saponins: assessing antiviral potential.

Porcine epidemic diarrhea virus (PEDV) causes deadly diarrhea in piglets, impacting the swine industry. Panax notoginseng saponins (PNS) inhibit PEDV replication in cells, potentially offering antiviral therapy options.

AntimicrobialPhytochemistry Panax notoginseng
Hu Y et al (2024).
Arch Virol.
DOI:
10.1007/s00705-024-06020-8
PubMed:
38565720
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