Green synthesis, antibacterial and antifungal evaluation of new thiazolidine-2,4-dione derivatives: molecular dynamic simulation, POM study and identification of antitumor pharmacophore sites.
Thiazolidine-2,4-dione derivatives with certain substituents showed strong antibacterial and antifungal activity, as well as potential as a targeted drug against multiple pathogens. Pharmacokinetics studies indicated drug-likeness and non-toxicity, contributing to the development of new drug candidates.
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- J Biomol Struct Dyn.
- PubMed:
- 37768136