Antimicrobial Studies

HPLC-ESI/MS-MS characterization of compounds in Dolomiaea costus extract and evaluation of cytotoxic and antiviral properties: molecular mechanisms underlying apoptosis-inducing effect on breast cancer.

Researchers identified the components in Dolomiaea costus extract and tested its effects on breast cancer cells and a virus. It has potential for cancer treatment and antiviral therapy.

El-Nashar HAS et al (2023).
BMC Complement Med Ther.
PubMed:
37803435

An in-vitro evaluation of antifungal, anti-lungcancer (A549), and anti-hyperglycemic activities potential of Andrographis paniculata (Burm. f.) flower extract.

Andrographis paniculata flower extract shows promise as an antifungal agent, inhibiting lung cancer cell growth and exhibiting anti-diabetic properties. Its bioactive compounds make it suitable for biomedical applications.

Phuong TN et al (2023).
Environ Res.
PubMed:
37783331

Structural characterization, antioxidant and antimicrobial activities of polysaccharide from Akebia trifoliata (Thunb.) Koidz stem.

This study analyzed the structure and properties of A. trifoliata (Thunb.) Koidz polysaccharides (ATKPs). ATKPs showed good thermal stability and exhibited strong antioxidant and antibacterial activities, making them a promising resource for food with medicinal value.

Li X et al (2023).
Colloids Surf B Biointerfaces.
PubMed:
37783040

Assessment of potential antimicrobial activity of Ocimum basilicum extract and chlorhexidine against Socransky's complex pathogens of oral cavity: An in vitro study.

Study tested the effectiveness of seed extract on the bacteria that cause periodontal disease. Findings could inform new treatments for periodontitis.

Khot AJP et al (2023).
J Indian Soc Periodontol.
PubMed:
37781327

Antioxidant, Cytotoxicity, Antimicrobial Activity, and In Silico Analysis of the Methanolic Leaf and Flower Extracts of Clitoria ternatea.

Extracts from have potent antibacterial, antibiofilm, and antioxidant properties, and high toxicity against brine shrimp. Compounds from the extracts exhibit potential as anti-medication, targeting antibiotic resistance proteins. These extracts could be valuable in combating antibiotic-resistant pathogens.

Islam MA et al (2023).
Biochem Res Int.
PubMed:
37780691

Furanonaphthoquinones, Diterpenes, and Flavonoids from Sweet Marjoram and Investigation of Antimicrobial, Bacterial Efflux, and Biofilm Formation Inhibitory Activities.

The chloroform extract from exhibited strong antibacterial and antifungal activity. Six compounds were isolated, including previously undescribed ones. Majoranaquinone showed high antibacterial effect, inhibition of efflux pumps, and inhibition of biofilm formation. It should be considered for antimicrobial effects of .

Abu Ghazal TS et al (2023).
ACS Omega.
PubMed:
37780020

Catharanthus roseus (L.) G. Don counteracts the ampicillin resistance in multiple antibiotic-resistant Staphylococcus aureus by downregulation of PBP2a synthesis.

Researchers evaluated the mechanism by which an extract from the root of the medicinal plant (L.) G. Don reverses ampicillin resistance in . The extract caused DNA damage, reduced plasmid band intensities, and decreased the expression of PBP2a protein, making the bacteria susceptible to the antibiotic ampicillin.

Shil A et al (2023).
Open Life Sci.
PubMed:
37772260