Antimicrobial Studies

Antimicrobial and biocompatibility nature of methanol extract of Lannea coromandelica bark and edible coating film preparation for fruit preservation.

Researchers studied the antimicrobial activity of Lannea coromandelica bark extract against fungi and bacteria, and found it to be effective. They also determined its biocompatibility and its potential for preserving fruit by creating an edible coating with chitosan. Coated fruit had improved quality compared to uncoated fruit.

Antimicrobial Citrus maxima
Chau TP et al (2023).
Environ Res.
DOI:
10.1016/j.envres.2023.117861
PubMed:
38070851

Danshensu inhibits SARS-CoV-2 by targeting its main protease as a specific covalent inhibitor and discovery of bifunctional compounds eliciting antiviral and anti-inflammatory activity.

Salvia miltiorrhiza and its active ingredient Danshensu have shown to inhibit SARS-CoV-2 and possess anti-inflammatory properties. Danshensu is a covalent inhibitor of the 3CL protease of SARS-CoV-2, making it a potential candidate for targeted drug development against COVID-19.

AntimicrobialCOVID-19Immunology Salvia
Wang R et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2023.128623
PubMed:
38070810

Antifungal effects of carvacrol, the main volatile compound in Origanum vulgare L. essential oil, against Aspergillus flavus in postharvest wheat.

Carvacrol, found in essential oils from Origanum vulgare L., can completely inhibit the growth of Aspergillus flavus in wheat grains, making it a potential biofumigant for preventing postharvest grain contamination. Carvacrol induces oxidative stress and damages the plasma membrane and DNA of A. flavus.

AntimicrobialPhytochemistry Origanum vulgare
Duan WY et al (2023).
Int J Food Microbiol.
DOI:
10.1016/j.ijfoodmicro.2023.110514
PubMed:
38070224

Green Synthesis of Chitosan-Capped Gold Nanoparticles Using Salvia officinalis Extract: Biochemical Characterization and Antimicrobial and Cytotoxic Activities.

In this study, researchers developed a green system to synthesize gold nanoparticles using sage leaf extract and chitosan. These nanoparticles showed effective inhibition of multidrug-resistant bacterial strains and potential for treating cancer at lower dosages than traditional drugs.

Antimicrobial Salvia officinalis
Al-Sarraj F et al (2023).
Molecules.
DOI:
10.3390/molecules28237762
PubMed:
38067495

Evaluation of antimicrobial, anti-inflammatory and cytotoxic effects of silver nanoparticles synthesised from Cynodon dactylon.

In this study, scientists used the extract of a plant to synthesize silver nanoparticles (AgNPs) in a simple and environmentally friendly way. The AgNPs were stable and showed antimicrobial and anti-inflammatory properties, but their cytotoxic effect on normal cells needs further investigation.

AntimicrobialImmunology Cynodon dactylon
Alex SB, M S S and M S L (2023).
Nat Prod Res.
DOI:
10.1080/14786419.2023.2290154
PubMed:
38058172

Alkaline lignins from Morinda citrifolia leaves are potential immunomodulatory, antitumor, and antimicrobial agents.

This study investigated the immunomodulatory, antitumor, and antimicrobial activities of lignin from Morinda citrifolia leaves. The results suggest that this lignin can activate immune cells, produce anti-inflammatory factors, and inhibit tumor and microbial growth. It has potential for developing biomedical and pharmaceutical products.

AntimicrobialCancerImmunology Morinda citrifolia
Cruz Filho IJ et al (2023).
An Acad Bras Cienc.
DOI:
10.1590/0001-3765202320221026
PubMed:
38055562

Evaluation of Physical Properties of Denture Base Resins Containing Silver Nanoparticles of Aloe barbadensis Miller, Morinda citrifolia, and Boesenbergia rotunda and Its Anti-microbial Effect: An In Vitro Study.

Adding plant extract silver nanoparticles to PMMA denture bases increased flexural strength and hardness, with finger root extract showing the highest antimicrobial activity against Candida albicans. This suggests that AgNPs can enhance denture base properties. (40 words)

Antimicrobial Morinda citrifolia
Kaul S et al (2023).
Cureus.
DOI:
10.7759/cureus.48260
PubMed:
38054116

Role of mitochondrial farnesyltransferase gene in the prevention of the food spoilage fungi Aspergillus flavus by the antimicrobial natural preservative perillaldehyde.

Researchers investigated the role of Cox10, an enzyme in the heme A synthesis pathway, in the growth and drug resistance of Aspergillus flavus. Deletion of cox10 affects growth and development, increases drug resistance, and triggers stress responses. Understanding these molecular mechanisms could help develop antifungal agents against A. flavus contamination.

AntimicrobialGenetics Perilla frutescens
Zhuo Q et al (2024).
Food Microbiol.
DOI:
10.1016/j.fm.2023.104422
PubMed:
38049276
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