The Therapeutic Potential of Two Egyptian Plant Extracts for Mitigating Dexamethasone-Induced Osteoporosis in Rats: Nrf2/HO-1 and RANK/RANKL/OPG Signals.
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- PubMed:
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Researchers identified new compounds from a herb and created derivatives. The compounds displayed anti-rheumatoid arthritis activity and inhibited inflammatory proteins.
This study reviewed clinical evidence on using herbal medicine to manage osteoporosis, which is a chronic skeletal disease causing low bone density and increased fracture risk.
Coptisine, a compound from Chinese herb, has anti-tumor effect but its impact on rheumatoid arthritis (RA) is unclear. This study investigates coptisine's ability to control synovial proliferation in RA and its mechanism(s).
This research investigates natural compounds from L. for their potential use in treating rheumatoid arthritis (RA). Through molecular docking and simulations, compounds β-sitosterol and colchicine show promising binding energies and stability, suggesting they could be effective anti-RA medications. Care because new treatment options for RA could be discovered.