Arthritis Studies

Isolation, structure modification, and anti-rheumatoid arthritis activity of isopimarane-type diterpenoids from Orthosiphon aristatus.

Researchers identified new compounds from a herb and created derivatives. The compounds displayed anti-rheumatoid arthritis activity and inhibited inflammatory proteins.

Luo YX et al (2024).
J Enzyme Inhib Med Chem.
PubMed:
38234133

Plant-derived natural medicines for the management of osteoporosis: A comprehensive review of clinical trials.

This study reviewed clinical evidence on using herbal medicine to manage osteoporosis, which is a chronic skeletal disease causing low bone density and increased fracture risk.

Karimi SM, Bayat M and Rahimi R (2023).
J Tradit Complement Med.
PubMed:
38223808

Coptisine inhibits aggressive and proliferative actions of fibroblast like synoviocytes and exerts a therapeutic potential for rheumatoid arthritis.

Coptisine, a compound from Chinese herb, has anti-tumor effect but its impact on rheumatoid arthritis (RA) is unclear. This study investigates coptisine's ability to control synovial proliferation in RA and its mechanism(s).

Xu F et al (2024).
Int Immunopharmacol.
PubMed:
38181676

Comprehending interaction mechanism of natural actives of Colchicum autumnale L. for rheumatoid arthritis using integrative chemoinformatic approaches.

This research investigates natural compounds from L. for their potential use in treating rheumatoid arthritis (RA). Through molecular docking and simulations, compounds β-sitosterol and colchicine show promising binding energies and stability, suggesting they could be effective anti-RA medications. Care because new treatment options for RA could be discovered.

H S S et al (2023).
J Biomol Struct Dyn.
PubMed:
38116745