Asthma Studies

CKD-497 inhibits NF-kB signaling and ameliorates inflammation and pulmonary fibrosis in ovalbumin-induced asthma and particulate matter-induced airway inflammatory diseases.

CKD-497, derived from rhizome and fruits, reduces inflammation and mucus production in asthma and pollution-induced lung inflammation. It inhibits proinflammatory cytokines and NF-kB pathway, potentially protecting against respiratory diseases.

AsthmaImmunology Schisandra chinensis
Kim H et al (2024).
Front Pharmacol.
DOI:
10.3389/fphar.2024.1428567
PubMed:
39170711

Exploring the In Vitro and In Vivo Therapeutic Efficacy of Juniperus oxycedrus Cade Oil: Antioxidant, Anti-inflammatory, and Anti-asthmatic Effects in an Allergic Asthma Model.

Cade oil shows strong antioxidant and anti-inflammatory effects in allergic asthma model. Potent scavenging activity against radicals, rich in polyphenols and flavonoids. Promising therapeutic potential for asthma treatment.

AsthmaImmunology Juniperus oxycedrus
Ahmida M et al (2024).
Cell Mol Biol (Noisy-le-grand).
DOI:
10.14715/cmb/2024.70.7.8
PubMed:
39097895

Euiin-Tang Attenuates Obesity-Induced Asthma by Resolving Metaflammation.

Euiin-tang reduces obesity-induced asthma in mice by suppressing inflammation and immune cell infiltration. It may be a potential therapeutic agent for obesity-related asthma.

AsthmaObesity Coix lacryma-jobi
Lee YE and Im DS (2024).
Pharmaceuticals (Basel).
DOI:
10.3390/ph17070853
PubMed:
39065704

Artemisia argyi essential oil alleviates asthma by regulating 5-LOX-CysLTs and IDO-1-KYN pathways: Insights from metabolomics.

Study found that AAEO may have potential therapeutic effects on asthma. Important for developing new treatments for this respiratory condition.

AsthmaPhytochemistry Artemisia argyi
Rong Y et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.118458
PubMed:
38871010

Fagopyrum Dibotrys Rhizoma regulates pulmonary lipid metabolic homeostasis and the ERK-cPLA(2) pathway to alleviate asthma in mice.

FDR, a traditional Chinese medicine, shows promise in treating asthma by targeting multiple factors with low side effects. Further research needed for exact mechanism.

Asthma Fagopyrum dibotrys
Wang X et al (2024).
Phytomedicine.
DOI:
10.1016/j.phymed.2024.155782
PubMed:
38851102

The Sensitization Differences of Pollen Allergen Components in Patients with Asthma and/or Rhinitis in Southern China.

Study identifies key pollen allergen components causing allergic asthma/rhinitis & explains cross-reactions. Important for understanding and treating pollen-related allergies.

Asthma Artemisia vulgarisQuercus alba
Xu C et al (2024).
Int Arch Allergy Immunol.
DOI:
10.1159/000538403
PubMed:
38705139

Integration of metabolomics and transcriptomics reveals the therapeutic mechanism underlying Chelidonium majus L. in the treatment of allergic asthma.

Study investigates mechanism of action of Chelidonium majus in relieving cough and asthma, important for potential use in modern medicine.

AsthmaGenetics Chelidonium majus
Wang R et al (2024).
Chin Med.
DOI:
10.1186/s13020-024-00932-y
PubMed:
38671520

In vivo determination of the anti-inflammatory and antioxidant effects of the aqueous extract of Syzygium aromaticum (clove) in an asthmatic rat model.

Study evaluated anti-inflammatory and antioxidant effects of clove extract on asthma in rats. AEC reduced lung oxidative stress and inflammation, showing potential for asthma treatment. Important for developing asthma therapies.

AsthmaImmunology Syzygium aromaticum
Ounaceur LS et al (2024).
Cell Mol Biol (Noisy-le-grand).
DOI:
10.14715/cmb/2024.70.3.5
PubMed:
38650159
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