Asthma Studies

Herbal Treatment of COPD and Asthma According to Persian Medicine: a Review of Current Evidence.

Study examines medicinal herbs as alternative treatment for COPD, due to unsatisfactory current therapies leading to adverse events like cardiovascular complications. Relevant for improving COPD management in labs.

Baniamerian R et al (2023).
Tanaffos.
PubMed:
38628881

Celastrol alleviates airway hyperresponsiveness and inflammation in obese asthma through mediation of alveolar macrophage polarization.

Celastrol from Tripterygium wilfordii roots reduces airway inflammation and hyperresponsiveness in obese asthma by balancing M1/M2 alveolar macrophage polarization, possibly through the PI3K/AKT pathway. This could lead to new therapeutic options for obese asthma.

Liang Y et al (2024).
Eur J Pharmacol.
PubMed:
38604543

Treatment with onion bulb extract both prevents and reverses allergic inflammation in a murine model of asthma.

Researchers studied the pharmacological actions of onion in treating airway diseases like asthma. Natural products like onion may be a safer and more cost-effective alternative to synthetic drugs.

El-Hashim AZ et al (2024).
Pharm Biol.
PubMed:
38584568

Demethylzeylasteral (T-96) Alleviates Allergic Asthma via Inhibiting MAPK/ERK and NF-κB Pathway.

Study on Demethylzeylasteral (T-96) from Tripterygium wilfordii Hook F shows its potential for treating allergic asthma by modulating immune response. Important for future asthma treatments.

Huang J et al (2024).
Int Arch Allergy Immunol.
PubMed:
38527438

Rapid screening and isolation of 5-lipoxygenase inhibitors in Inonotus obliquus and mechanism of action in the treatment of asthma.

Study developed a new method to efficiently screen and isolate potential active ingredients in Inonotus obliquus for treatment of asthma. Utilized UF mass spectrometry and molecular docking to identify inhibitors of 5-LOX, followed by isolation of betulin, lanosterol, and quercetin.

Yun H et al (2024).
J Sep Sci.
PubMed:
38466162

Preparation and in vivo evaluation of nano sized cubosomal dispersion loaded with Ruta graveolens extracts as a novel approach to reduce asthma-mediated lung inflammation.

Study finds extract with anti-asthmatic effects, reducing symptoms and improving lung function in rats. Extract shows antioxidant, anti-inflammatory activities and induces autophagy while inhibiting apoptosis. Could be developed as anti-allergic asthma drug.

Alyami MH et al (2024).
Saudi Pharm J.
PubMed:
38352238

Novel insights into the anti-asthmatic effect of Raphanus sativus L. (Raphani Semen): Targeting immune cells, inflammatory pathways and oxidative stress markers.

Researchers studied the medicinal plant Raphanus sativus L., commonly used for inflammation and asthma. Their findings could inform the development of new treatments for these conditions.

Gul H et al (2024).
J Ethnopharmacol.
PubMed:
38336182
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