Cardiology Studies

Oroxylin A, a broad‑spectrum anticancer agent, relieves monocrotaline‑induced pulmonary arterial hypertension by inhibiting the Warburg effect in rats.

Oroxylin A (OA) inhibits glycolytic enzymes to treat liver cancer; it also decreases pulmonary arterial hypertension (PAH) in rats by reducing the Warburg effect of abnormal glucose metabolism. OA shows potential as a protective treatment for PAH.

Wang Y et al (2024).
Mol Med Rep.
PubMed:
39219283

Cardioprotective effect of chelidonic acid against doxorubicin-induced cardiac toxicity in rats.

Study shows CA protects against doxorubicin-induced heart damage. CA is a compound in celandine plant. Potential for new heart protection treatment.

Khairnar SI, Kulkarni YA and Singh K (2024).
Rev Port Cardiol.
PubMed:
39216530

Ligustilide alleviates oxidative stress during renal ischemia-reperfusion injury through maintaining Sirt3-dependent mitochondrial homeostasis.

Researchers explored the potential of Ligustilide (LIG) to protect mitochondrial function and potentially ameliorate renal ischemia-reperfusion injury during transplantation. Understanding LIG's targets and mechanisms is important for improving patient outcomes.

Xia K et al (2024).
Phytomedicine.
PubMed:
39216302

Artemisia vulgaris Extract as a Novel Therapeutic Approach for Reversing Diabetic Cardiomyopathy in a Rat Model.

Methanolic extract of [plant] shows potential in reversing cardiac remodeling in diabetic cardiomyopathy, improving heart function and reducing side effects compared to current anti-hyperglycemic therapies.

Liza et al (2024).
Pharmaceuticals (Basel).
PubMed:
39204151

Ethanolic Extracts of Cupressaceae Species Conifers Provide Rapid Protection against Barium Chloride-Induced Cardiac Arrhythmia.

Certain Cupressaceae species have active antiarrhythmic components, providing potential for preventing cardiac arrhythmias and reducing sudden cardiac death. Importance lies in developing new, effective and safe treatments.

Zeng MT et al (2024).
Pharmaceuticals (Basel).
PubMed:
39204108

Demonstration of the Protective Effect of Vinpocetine in Diabetic Cardiomyopathy.

Study on Vinpocetine's effects on diabetic cardiomyopathy showed it reduced heart damage, improved markers and structure. Vinpocetine may be a promising treatment for diabetic heart disease.

Erciyes D et al (2024).
J Clin Med.
PubMed:
39200779

Melastoma dodecandrum lour. Protects against cerebral ischemia-reperfusion injury by ameliorating oxidative stress and endoplasmic reticulum stress.

Melastoma dodecandrum Lour. shows promise in treating cerebral ischemia-reperfusion injury. Its traditional use by the She ethnic group suggests potential efficacy in promoting blood circulation and removing blood stasis. Further research is needed to understand its therapeutic effects and mechanisms.

Liu S et al (2024).
J Ethnopharmacol.
PubMed:
39182701
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