Cardiology Studies

Gastrodin against oxidative stress-inflammation crosstalk via inhibiting mtDNA/TLR9 and JAK2/STAT3 signaling to ameliorate ischemic stroke injury.

Gastrodin protects against stroke-induced inflammation and mitochondrial dysfunction by inhibiting JAK2/STAT3 signaling pathway, making it a potential therapy for cerebral ischemia.

Zhang M et al (2024).
Int Immunopharmacol.
PubMed:
39182268

Prophylactic impacts of Lagenaria siceraria against cardiomyopathy induced by doxorubicin in a rat model.

Researchers studied the potential of resveratrol to protect against doxorubicin-induced heart damage in cancer treatment. Result: resveratrol showed promise as a protective agent. Important for improving cancer treatment outcomes.

Almohmadi NH et al (2024).
Open Vet J.
PubMed:
39175975

Soursop leaf extract and fractions protects against L-NAME-induced hypertension and hyperlipidemia.

Study showed leaf extracts have potential anti-hypertensive and antihyperlipidemic properties. Important for potential new treatments for high blood pressure and high cholesterol.

Nsor OO et al (2024).
Front Nutr.
PubMed:
39171117

Fundamental characteristics of ultrasonic green formulations using Avena sativa L. extract-mediated gold nanoparticles and electroconductive nanofibers for cardiovascular nursing care.

Eco-friendly gold nanoparticles in nanofibers enhance heart tissue repair. Promising for treating heart failure and improving cardiovascular nursing care.

Wei X, Jiang X and Li H (2024).
Heliyon.
PubMed:
39170527

Geniposide for treating atherosclerotic cardiovascular disease: a systematic review on its biological characteristics, pharmacology, pharmacokinetics, and toxicology.

Geniposide from Gardenia jasminoides Ellis shows potential in managing atherosclerotic cardiovascular disease by reducing inflammation, improving lipid metabolism, and preventing thrombosis. It also has antioxidant and anti-apoptotic effects. This review outlines its pharmacological mechanisms and clinical applications.

Li D et al (2024).
Chin Med.
PubMed:
39164773

Safflower Alleviates Pulmonary Arterial Hypertension by Inactivating NLRP3: A Combined Approach of Network Pharmacology and Experimental Verification.

Study explores how safflower treats pulmonary arterial hypertension. Fill gaps in knowledge on mechanisms behind safflower's effectiveness. Relevant for developing treatments for PAH.

Ding S et al (2024).
Clin Respir J.
PubMed:
39155275

Tapping the potential of Calotropis procera hairy roots for cardiac glycosides production and their identification using UHPLC/QTOF-MS.

Scientists established hairy root cultures from different explants of a plant using a specific strain. High transformation frequency achieved. Identified 10 cardiac glycosides in hairy root extracts. Valuable for production of cardiac glycosides and future research.

Djerdjouri A et al (2024).
3 Biotech.
PubMed:
39144068

Green Synthesis and Chemical Characterization of Silver Nanoparticles by Tribulus terrestris for the Treatment of Myocardial Infarction.

AgNPs exhibit cardioprotective properties on isoproterenol-induced myocardial infarction by inhibiting NF-κB signaling and activating PPAR-γ, reducing inflammation and cell death. This research introduces a potential therapeutic approach for treating myocardial infarction.

Huang Y et al (2024).
Biol Trace Elem Res.
PubMed:
39134771
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