Cardiology Studies

Baicalin ameliorates angiotensin II-induced cardiac hypertrophy and mitogen-activated protein kinase signaling pathway activation: A target-based network pharmacology approach.

Baicalin from Scutellaria baicalensis helps lower blood pressure and protects the heart. Targets related to cardiac hypertrophy and signaling pathways were identified, showing improved cardiac function in mice and cells by reducing cardiac hypertrophy markers and MAPK pathway activation. It can be beneficial for hypertension-related heart issues.

COVID-19Cardiology Scutellaria baicalensis
Cheng Y et al (2024).
Eur J Pharmacol.
DOI:
10.1016/j.ejphar.2024.176876
PubMed:
39127302

Jin-Xin-Kang alleviates heart failure by mitigating mitochondrial dysfunction through the Calcineurin/Dynamin-Related Protein 1 signaling pathway.

JXK, a traditional Chinese herbal formula, effectively treats chronic heart failure (CHF) with seven medicinal herbs. While its clinical efficacy is proven, the specific mechanisms remain unknown. Further research is needed for potential cardiac treatment advancements.

Cardiology Cinnamomum cassiaIlex pubescensLeonurus japonicusSalviaSalvia miltiorrhiza
Lin L et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.118685
PubMed:
39127116

Investigation of the cardioprotective effects of Momordica charantia in the isoproterenol-induced myocardial infarction model in rats.

Study tested Momordica charantia on rats with induced heart attacks to see if it had protective effects. MC was found to have antioxidant and anti-inflammatory properties, potentially beneficial for treating MI.

Cardiology Momordica charantia
Karadeniz B and Beyazcicek O (2024).
Biomed Pharmacother.
DOI:
10.1016/j.biopha.2024.117274
PubMed:
39116781

Trigonelline, a Fenugreek Bioactive protects Heart tissue against alcohol intoxication: An in-vivo study focusing on antioxidant perspective.

Fenugreek has diverse health benefits like antioxidants, anti-diabetic, and lowering cholesterol. Incorporating it into lab research could lead to potential new treatments.

CardiologyImmunology Trigonella foenum
Sekhar MG, Ramudu Shanmugam K and Chakrapani IS (2024).
J Ayurveda Integr Med.
DOI:
10.1016/j.jaim.2024.100963
PubMed:
39116705

A class of geranylquinol-derived polycyclic meroterpenoids from Arnebia euchroma against heart failure by reducing excessive autophagy and apoptosis in cardiomyocytes.

Scientists isolated new compounds from a plant, studied their structures and biosynthetic pathways, and found some had cardioprotective effects on heart cells by modulating cellular pathways. Important for drug development and understanding cardiac health.

Cardiology Arnebia euchroma
Zhao LH et al (2024).
Bioorg Chem.
DOI:
10.1016/j.bioorg.2024.107691
PubMed:
39116524

Natural product-based treatment potential for type 2 diabetes mellitus and cardiovascular disease.

Researchers investigated the link between type 2 diabetes and cardiovascular disease, finding common risk factors and proposing natural supplement treatment. This could be a promising preventive and therapeutic option for both diseases.

CardiologyDiabetes Melissa officinalisTerminalia chebula
Shrivastav D et al (2024).
World J Diabetes.
DOI:
10.4239/wjd.v15.i7.1603
PubMed:
39099809

Exploring faba beans (Vicia faba L.): bioactive compounds, cardiovascular health, and processing insights.

Scientists reviewed the health benefits of faba beans, focusing on bioactive compounds and processing methods. Understanding these can improve cardiovascular health, reduce cancer risk, and utilize processing water in food production.

Cardiology Vicia faba
Feng Z et al (2024).
Crit Rev Food Sci Nutr.
DOI:
10.1080/10408398.2024.2387330
PubMed:
39097752

Phytochemical analysis and cardiovascular protective effect of four herbal medicines with functional food properties (Four Huaiqing Chinese Medicine).

Chinese herbs Libosch, Bl., Thunb, and Ramat have shown potential as functional food materials. Identified constituents are mainly flavones and aromatic compounds. They demonstrated significant effects in reducing cell injury markers and improving cell function. These herbs could be beneficial for reducing cell apoptosis and improving cell migration capacity.

CardiologyPhytochemistry Achyranthes bidentataChrysanthemum morifolium
Li Y et al (2024).
Nat Prod Res.
DOI:
10.1080/14786419.2024.2381659
PubMed:
39069726
1 2 3 4 13 76