Cardiology Studies

Corrigendum: Cardioprotective effect of Sanguisorba minor against isoprenaline-induced myocardial infarction in rats.

Researchers analyzed the effects of a novel drug on heart failure in mice. Results demonstrate potential for clinical application in treating heart conditions. Important for advancing cardiovascular medicine.

Hosseini A et al (2024).
Front Pharmacol.
PubMed:
38449813

Phillyrin improves myocardial remodeling in salt-sensitive hypertensive mice by reducing endothelin1 signaling.

Phillyrin from Forsythia suspensa protects the heart from strain caused by chronic hypertension. This study explores how phillyrin can prevent hypertension-induced myocardial remodeling in mice.

Luo Q et al (2024).
J Pharm Pharmacol.
PubMed:
38447186

The anti-apoptotic role of Ginkgolide B via mitochondrial permeability transition pore inhibition in retinal ischemia-reperfusion.

Ginkgolide B from Ginkgo biloba protects mitochondria in glaucoma, reducing cell death. Could be a treatment for acute primary angle-closure glaucoma.

Wang X et al (2024).
Biochem Biophys Res Commun.
PubMed:
38442447

Bacillus safensis filtrate-based ZnO nanoparticles control black heart rot disease of apricot fruits by maintaining its soluble sugars and carotenoids.

Zinc oxide nanoparticles synthesized from Bacillus safensis can effectively control black heart rot in apricot, inhibiting fungal growth and improving fruit quality by maintaining nutrient content. Farmers can easily apply these nanoparticles in powder form to protect their crops.

Farhana et al (2024).
World J Microbiol Biotechnol.
PubMed:
38441800

Investigating the Mechanism of Chinese Medicine Formula AACO Against Chronic Heart Failure by Network Pharmacology Analysis and Experimental Validation.

This study shows that a TCM formula containing AACO has potential benefits for treating chronic heart failure. Consider integrating into lab protocols for further investigation.

Lu C et al (2024).
Altern Ther Health Med.
PubMed:
38430163

Hydroxysafflor Yellow A Exerts Neuroprotective Effects by Inhibiting Protein Carbonyl Formation in Cerebral Ischemia-Reperfusion Injury.

HSYA from Carthamus tinctorius protects against cerebral ischemia-reperfusion injury by reducing protein carbonylation, improving neurological function, and enhancing antioxidant capacity through ONOO- scavenging and suppressing protein oxidation.

Zhao R et al (2024).
Altern Ther Health Med.
PubMed:
38430158

FDA compound library screening Baicalin upregulates TREM2 for the treatment of cerebral ischemia-reperfusion injury.

TREM2 upregulation by Baicalin reduces inflammation and oxidative stress in acute ischemic stroke, showing promise for treatment efficacy in both in vitro and in vivo models.

Wang H et al (2024).
Eur J Pharmacol.
PubMed:
38428662

Intermittent fasting along with hydroalcoholic extract of Centella-asiatica ameliorates sub-acute hypoxia-induced ischemic stroke in adult zebrafish.

Study shows Centella-Asiatica extract and intermittent fasting protect brain from hypoxia-induced damage in zebrafish. Benefits include antioxidant, anti-inflammatory, and neuroprotective effects, along with improved mitochondrial function. Useful for stroke prevention research and potential clinical applications.

Bindal P et al (2024).
Comp Biochem Physiol C Toxicol Pharmacol.
PubMed:
38428624