Cardiology Studies

Cardioprotective Effect of Hydroalcohol Extract of Andaliman (Zanthoxylum acanthopodium DC.) Fruits on Doxorubicin-Induced Rats.

Andaliman fruit extract has cardioprotective effects, increasing SOD levels and decreasing BNP and cTnT levels in doxorubicin-induced rats. It can repair heart tissue damage and has potential for development.

Dalimunthe A et al (2024).
Pharmaceuticals (Basel).
PubMed:
38543145

Neferine Pretreatment Attenuates Isoproterenol-Induced Cardiac Injury Through Modulation of Oxidative Stress, Inflammation, and Apoptosis in Rats.

Neferine, derived from lotus seeds, protects against heart damage in rats induced with heart attacks. It improves cardiac function, lipid profiles, and reduces inflammation and apoptosis through various signaling pathways. Neferine shows promising medicinal effects for cardiovascular health.

Sun X et al (2024).
Appl Biochem Biotechnol.
PubMed:
38526658

Protective effect of ginsenoside Rb1 against aconitine cardiotoxicity studied by myocardial injury, action potential, and calcium signaling.

Ginsenoside Rb1 can mitigate aconitine-induced cardiotoxicity by reducing myocardial damage and restoring action potential and calcium signaling balance. This study shows potential for using Rb1 as a detoxifying agent in traditional Chinese medicine.

Zhang C et al (2024).
Toxicon.
PubMed:
38519012

Cytisine-N-methylene-(5,7,4(')-trihydroxy)- isoflavone ameliorates ischemic stroke-induced brain injury in mouse by regulating the oxidative stress and BDNF-Trkb/Akt pathway.

LY01, from Sophora alopecuroides L, shows neuroprotection and potential for ischemic stroke treatment. Further research needed for mechanism and efficacy.

Li Y, Fan F and Liu Q (2024).
Eur J Pharmacol.
PubMed:
38493912

Synergistic amelioration between Ligusticum striatum DC and borneol against cerebral ischemia by promoting astrocytes-mediated neurogenesis.

LCH and BO combo improves neurogenesis for ischemic stroke. Mechanism of synergy needs clarification for effective treatment in the lab.

Zhang X et al (2024).
J Ethnopharmacol.
PubMed:
38492790

The Potential of Natural Products in the Management of Cardiovascular Disease.

Research suggests natural products may offer alternative, cost-effective treatments for cardiovascular diseases, with potential benefits including anti-oxidant and anti-cholesterol effects. Explore their potential alongside conventional therapies.

Singhai H et al (2024).
Curr Pharm Des.
PubMed:
38477208

Protective role of forsythoside B in Kawasaki disease-induced cardiac injury: Inhibition of pyroptosis via the SIRT1-NF-κB-p65 signaling pathway.

FTS-B from Forsythia suspensa inhibits NF-κB through SIRT1, reducing inflammatory damage in Kawasaki disease models. SIRT1-NF-κB-p65 pathway may be a promising therapeutic target for KD treatment.

Yang Y et al (2024).
Chem Biol Interact.
PubMed:
38471628