Dietary Supplement with Tribulus terrestris L. Extract Exhibits Protective Effects on Ischemic Stroke Rats.

Researchers found that gross saponins of Tribulus terrestris extract have a protective effect against ischemic stroke, although the mechanism is not fully understood. Relevant for potential stroke prevention strategies.

Guo W et al (2023).

Mol Nutr Food Res.

DOI:

10.1002/mnfr.202300447

PubMed:

37876150

A comparative analysis of phytochemicals, metal ions, volatile metabolites in heart wood, stem bark and leaves of Salix alba L. along with invitro antioxidant, antacid, antimicrobial activities for sake of environment conservation by substitution of stem bark with leaf.

Salix alba L. leaves are abundant in micronutrients, essential metals, possess strong antibacterial activity and higher antacid activity compared to stem bark and heartwood.

Gandhi Y et al (2023).

Chem Biodivers.

DOI:

10.1002/cbdv.202301234

PubMed:

37867394

Blood pressure lowering effects of Vernonia amygdalina Del. Aqueous fraction on hypertensive Wistar Kyoto rats.

Researchers investigated the blood pressure-lowering effect of Vernonia amygdalina leaf's aqueous fraction (VALAF) in a hypertensive model. VALAF contains secondary metabolites with antioxidant, anticancer, antidiabetic, and hepatoprotective properties.

Juwita DA et al (2023).

J Complement Integr Med.

DOI:

10.1515/jcim-2022-0416

PubMed:

37831720

Study on the anti-mitochondrial apoptosis mechanism of Erigeron breviscapus injection based on UPLC-Q-TOF-MS metabolomics and molecular docking in rats with cerebral ischemia-reperfusion injury.

Zhang J et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.117310

PubMed:

37827296

Evaluating the role of Ginkgo biloba extract in the secondary prevention of Acute Ischemic Stroke with cerebral microbleeds by Quantitative Susceptibility Mapping（QSM）.

EGb 761, a Ginkgo biloba extract, has anti-inflammatory and thrombotic effects. In a study, EGb combined with Aspirin improved blood oxygen saturation in ischemic stroke patients with microbleeds. This combo could be effective for long-term secondary prevention.

Lan W et al (2023).

Int J Neurosci.

DOI:

10.1080/00207454.2023.2268264

PubMed:

37812205

Plasma metabonomic study on the effect of Para‑hydroxybenzaldehyde intervention in a rat model of transient focal cerebral ischemia.

Para-hydroxybenzaldehyde (PHBA) protected against cerebral ischemia in rats by improving neurological function, reducing infarction area, and increasing neuron number. Metabolic analysis identified key pathways and PHBA increased autophagy, offering potential stroke therapies.

Yu X et al (2023).

Mol Med Rep.

DOI:

10.3892/mmr.2023.13111

PubMed:

37800608

Saponins of Panax japonicus ameliorates cardiac aging phenotype in aging rats by enhancing basal autophagy through AMPK/mTOR/ULK1 pathway.

Huang H et al (2023).

Exp Gerontol.

DOI:

10.1016/j.exger.2023.112305

PubMed:

37797916

Wild and cultivated olive trees: Nutraceutical insights of extra virgin olive oils in cardiovascular and ocular diseases.

Extra virgin olive oil (EVOO) and ACE oil from wild olive variety contain bioactive molecules that have anti-inflammatory, antioxidant, anti-cancer properties. They can help prevent cardiovascular diseases, ocular diseases, and have potential as prebiotic compounds.

Reyes-Goya C et al (2023).

Biochim Biophys Acta Mol Basis Dis.

DOI:

10.1016/j.bbadis.2023.166904

PubMed:

37793462