Cardiology Studies

Efficacy and safety of Ginkgo biloba dropping pills in the treatment of coronary heart disease with stable angina pectoris and depression: study protocol for a randomised, placebo-controlled, parallel-group, double-blind and multicentre clinical trial.

A study found that GBDPs derived from GBE can improve angina frequency and quality of life in patients with stable angina pectoris and depression symptoms, suggesting potential usefulness as treatment.

CardiologyNeuroscience Ginkgo biloba
Wu T et al (2023).
BMJ Open.
DOI:
10.1136/bmjopen-2021-055263
PubMed:
37164472

Nobiletin attenuates monocrotaline-induced pulmonary arterial hypertension through PI3K/Akt/STAT3 pathway.

This study examines the potential of nobiletin, found in orange peel, to relieve pulmonary arterial hypertension induced by monocrotaline and investigates how it works.

CardiologyImmunology Citrus sinensis
Yin Q et al (2023).
J Pharm Pharmacol.
DOI:
10.1093/jpp/rgad045
PubMed:
37158759

Protective effects of the Terminalia bellirica tannin-induced Nrf2/HO-1 signaling pathway in rats with high-altitude pulmonary hypertension.

Tannins in Terminalia bellirica protect against oxidative stress and inflammation induced by high-altitude hypoxia, potentially preventing high-altitude pulmonary hypertension.

Cardiology Terminalia bellirica
Aimaier S et al (2023).
BMC Complement Med Ther.
DOI:
10.1186/s12906-023-03981-2
PubMed:
37149589

[Impact of essential oil vapors inhalation on blood pressure in patients with hypertension].

Research on essential oils as antihypertensive agents is limited, making it difficult to determine their effectiveness in lowering blood pressure.

CardiologyPhytochemistry Nepeta cataria
Yarosh AM et al (2023).
Vopr Kurortol Fizioter Lech Fiz Kult.
DOI:
10.17116/kurort202310002122
PubMed:
37141519

Engeletin alleviates cerebral ischemia reperfusion-induced neuroinflammation via the HMGB1/TLR4/NF-κB network.

Engeletin, derived from Smilax glabra rhizomilax, has neuroprotective effects in rats with cerebral ischemia reperfusion injury, reducing deficits, infarct size, inflammation, and apoptosis. It suppresses the HMGB1/TLR4/NF-κB inflammatory network.

CardiologyImmunologyNeuroscience Smilax glabra
Xu Y et al (2023).
J Cell Mol Med.
DOI:
10.1111/jcmm.17758
PubMed:
37132060

Sanhua decoction: Current understanding of a traditional herbal recipe for stroke.

Sanhua decoction (SHD), a traditional Chinese medicine with over 40 bioactive compounds, shows promise in treating ischemic stroke by suppressing inflammation, protecting the blood brain barrier, inhibiting apoptosis, scavenging oxygen free radicals, and more. Large-scale clinical trials are needed to confirm its efficacy and understand its mechanisms.

CardiologyNeuroscience Citrus aurantiumHansenia weberbaueriana
Zheng L et al (2023).
Front Neurosci.
DOI:
10.3389/fnins.2023.1149833
PubMed:
37123364

Ginkgolide C attenuates cerebral ischemia/reperfusion-induced inflammatory impairments by suppressing CD40/NF-κB pathway.

Ginkgo biloba has been used in Chinese medicine for cardiovascular diseases. Ginkgolide C shows promise in reducing inflammation in cerebral ischemia/reperfusion injury.

CardiologyImmunology Ginkgo biloba
Li B et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.116537
PubMed:
37094696

Exploring the molecular mechanism of Nux Vomica in treating ischemic stroke using network pharmacology and molecular docking methods.

Scientific study investigates Nux Vomica's pharmacological mechanism for treating ischemic stroke, highlighting its potential as a therapeutic option for brain damage by regulating inflammatory responses.

CardiologyNeuroscience Strychnos nux-vomica
Zhang C et al (2023).
Medicine (Baltimore).
DOI:
10.1097/MD.0000000000033625
PubMed:
37083769
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